Evidence map›Paper›PMID 24449829›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2014

TGF-β and lung fluid balance in ARDS.

James A Frank, Michael A Matthay

Open access · bronzeAbstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Regulation of inflammatory lung injury and repair by transforming growth factors.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  3. The lung microbiome in interstitial lung disease.Breathe (Sheffield, England) · 2025
    Review
  4. Mechanical ventilation energy analysis: Recruitment focuses injurious power in the ventilated lung.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
  7. In well-differentiated primary human bronchial epithelial cells, TGF-American journal of physiology. Lung cellular and molecular physiology · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James A FrankDepartments of Medicine and Anesthesia, Cardiovascular Research Institute, University of California, San Francisco, CA 94143.
Michael A Matthay
University of California, San Francisco · US

Funding

Resolution of Clinical Lung InjuryR37HL051856 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHAY, MICHAEL A. · 2006 to 2015
$3.9M
Regulation of alveolar epithelial barrier function by claudinsR01HL088440 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI FRANK, JAMES A · 2007 to 2011
$2.3M
Claudin-18 deficiency in the pathogenesis of asthmaR21HL111707 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI FRANK, JAMES A · 2012 to 2013
$399k
Regulation of alveolar barrier function by claudinsR56HL088440 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI FRANK, JAMES A · 2013 to 2013
$380k
NHLBI NIH HHS R01 HL088440NHLBI NIH HHS R21 HL111707NHLBI NIH HHS R37 HL051856NHLBI NIH HHS R56 HL088440
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationAcute Lung InjuryAnimalsEpithelial Sodium ChannelsFemaleHumansMaleTransforming Growth Factor betaEpithelial Sodium ChannelsTransforming Growth Factor beta

Identifiers

PMID24449829
PMCPMC3903208
OpenAlexW2039150070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.