Evidence map›Paper›PMID 24449017›Full record

ArticlePrimary care respiratory journal : journal of the General Practice Airways Group2014

Are GOLD ABCD groups better associated with health status and costs than GOLD 1234 grades? A cross-sectional study.

Melinde R S Boland, Apostolos Tsiachristas, Annemarije L Kruis, Niels H Chavannes, Maureen P M H Rutten-van Mölken

Open access · bronzeAbstract read
In one paragraph

Article in Primary care respiratory journal : journal of the General Practice Airways Group, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  7. Article
  8. The annual direct costs of stable COPD in Greece.International journal of chronic obstructive pulmonary disease · 2018
    Article
  9. Observational
  10. The pharmacological cost of COPD during Greek economic crisis.International journal of chronic obstructive pulmonary disease · 2017
    Article
  11. Implications of the GOLD COPD Classification and Guidelines.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2015
    Article
  12. A golden goal in 2010, and another GOLD in 2014 in primary care, or vice versa.Primary care respiratory journal : journal of the General Practice Airways Group · 2014
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Melinde R S BolandInstitute for Medical Technology Assessment, Erasmus University Rotterdam, Rotterdam, The Netherlands • Department of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Apostolos Tsiachristas
Annemarije L Kruis
Niels H Chavannes
Maureen P M H Rutten-van Mölken
Erasmus University Rotterdam · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate the association of the GOLD ABCD groups classification with costs and health-related quality of life (HR-QoL) and to compare this with the GOLD 1234 grades classification that was primarily based on lung function only.

methodsIn a cross-sectional study, we selected patients diagnosed with chronic obstructive pulmonary disease (COPD) from electronic medical records of general practices. Multi-level analysis was used with costs (medication, primary care, healthcare, societal), diseasespecific and generic HR-QoL as independent variables. Either the new or the old GOLD stages were included in the analysis together with several covariates (age, gender, living situation, co-morbidity, self-efficacy, smoking, education, employment).

results611 patients from 28 general practices were categorised as GOLD-A (n=333), GOLD-B (n=110), GOLD-C (n=80) and GOLD-D (n=88). Patients in the GOLD-B and GOLD-D groups had the highest prevalence of co-morbidities and the lowest level of physical activity, self-efficacy, and employment. The models with GOLD ABCD groups were more strongly related to and explained more variance in costs and in disease-specific and generic HR-QoL than the models with GOLD 1234 grades. The mean Clinical COPD Questionnaire score worsened significantly, with scores 1.04 (GOLD-B), 0.4 (GOLD-C) and 1.21 (GOLD-D) worse than for patients in GOLD-A. Healthcare costs per patient were significantly higher in GOLD-B (72%), GOLD-C (74%) and GOLD-D (131%) patients than in GOLD-A patients.

conclusionsThe GOLD ABCD groups classification is more closely associated with costs and HR-QoL than the GOLD 1234 grades classification. Furthermore, patients with GOLD-C had a better HR-QoL than those with GOLD-B but the costs of the two groups did not differ.

Indexed as

Health StatusQuality of LifeAgedCosts and Cost AnalysisCross-Sectional StudiesFemaleHumansMalePulmonary Disease, Chronic Obstructive

Identifiers

PMID24449017
PMCPMC6442289
OpenAlexW2110864183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.