ArticleGenome biology and evolution2014
Horizontal gene transfer and redundancy of tryptophan biosynthetic enzymes in dinotoms.
Article in Genome biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Functional division of labor in motility, lignocellulose digestion, and nitrogen metabolism revealed for the Mixotricha paradoxa holobiont.The ISME journal · 2025Article
- Genetic Context Significantly Influences the Maintenance and Evolution of Degenerate Pathways.Genome biology and evolution · 2021Article
- Metabolomics Reveals Minor Tambjamines in a Marine Invertebrate Food Chain.Journal of natural products · 2021Article
- A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites.PLoS biology · 2019Article
- In the beginning was the word: How terminology drives our understanding of endosymbiotic organelles.Microbial cell (Graz, Austria) · 2019Article
- Homoeolog expression bias in allopolyploid oleaginous marine diatom Fistulifera solaris.BMC genomics · 2018Article
- Major transitions in dinoflagellate evolution unveiled by phylotranscriptomics.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Evolution of the Tetrapyrrole Biosynthetic Pathway in Secondary Algae: Conservation, Redundancy and Replacement.PloS one · 2016Article
- Integration of plastids with their hosts: Lessons learned from dinoflagellates.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
- Extensive horizontal gene transfer, duplication, and loss of chlorophyll synthesis genes in the algae.BMC evolutionary biology · 2015Article
- Phylogenomic study indicates widespread lateral gene transfer in Entamoeba and suggests a past intimate relationship with parabasalids.Genome biology and evolution · 2014Article
- Evidence for the retention of two evolutionary distinct plastids in dinoflagellates with diatom endosymbionts.Genome biology and evolution · 2014Article
- Complex Ancestries of Isoprenoid Synthesis in Dinoflagellates.The Journal of eukaryotic microbiologyArticle
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Authors and funding
2 authors.
Funding
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Abstract
A tertiary endosymbiosis between a dinoflagellate host and diatom endosymbiont gave rise to "dinotoms," cells with a unique nuclear and mitochondrial redundancy derived from two evolutionarily distinct eukaryotic lineages. To examine how this unique redundancy might have affected the evolution of metabolic systems, we investigated the transcription of genes involved in biosynthesis of the amino acid tryptophan in three species, Durinskia baltica, Kryptoperidinium foliaceum, and Glenodinium foliaceum. From transcriptome sequence data, we recovered two distinct sets of protein-coding transcripts covering the entire tryptophan biosynthetic pathway. Phylogenetic analyses suggest a diatom origin for one set of the proteins, which we infer to be expressed in the endosymbiont, and that the other arose from multiple horizontal gene transfer events to the dinoflagellate ancestor of the host lineage. This is the first indication that these cells retain redundant sets of transcripts and likely metabolic pathways for the biosynthesis of small molecules and extend their redundancy to their two distinct nuclear genomes.
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