ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2014
Cartilage differentiation in ependymoma: histogenetic considerations on a new case.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- An anaplastic ependymoma with chondroid metaplasia after stereotactic radiosurgery: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Chondro-Osseous Metaplasia in Ependymoma: A Rare Histopathological Finding.Case reports in pathology · 2020Article
- Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature.Case reports in pathology · 2016Article
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6 authors at 1 institution in 1 country.
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Abstract
The presence of cartilage in gliomas is a very unusual finding and has been mainly reported in ependymomas and in astrocytomas. A derivation of cartilage from neuroepithelial cells through a neuroepithelial-mesenchymal transition or directly from blood vessel-associated multipotent stromal elements has been proposed. We herein describe a further case of ependymoma with the presence of cartilage in a child affected by a tumor in the posterior fossa. In this case, only the last recurrence, characterized by focal areas of anaplasia, contained a nodule of cartilage. The immunohistochemical expression of fibronectin, tenascin-C, and CD44 was investigated, and the possible role of these molecules in the process of cartilage formation is discussed. Moreover, the literature on the subject is reviewed.
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