Evidence map›Paper›PMID 24448314›Full record

ReviewCardiovascular research2014

Maternal cardiac metabolism in pregnancy.

Laura X Liu, Zolt Arany

Open access · bronzeAbstract readReview
In one paragraph

Review in Cardiovascular research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 136 citations in OpenAlex.

  1. Trial
  2. Article
  3. Peripartum-Associated Heart Failure Develops Independently of RHOT Proteins.International journal of molecular sciences · 2026
    Article
  4. Article
  5. Cardiovascular complications of pregnancy.The Journal of clinical investigation · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. ISUOG Consensus Statement on maternal hemodynamic assessment in hypertensive disorders of pregnancy and fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Article
  11. Longitudinal changes in cardiovascular and sympathetic neural responses to static handgrip exercise throughout pregnancy.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  12. Review
  13. Review
  14. Maternal cardiovascular research and education should be prioritized in the United States.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Cardiac mitochondrial metabolism during pregnancy and the postpartum period.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Laura X LiuCardiovascular Institute, and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Zolt Arany
Beth Israel Deaconess Medical Center · USCenter for Vascular Biology Research · US

Funding

PGC-1 Coactivators in Muscle Angiogenesis IschemiaR01HL094499 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI ARANY, ZOLTAN P · 2010 to 2018
$3.7M
Aging and Cardioprotection by Skeletal Muscle PGC-1alpha in Endurance ExerciseF31AG041598 · NIA · HARVARD MEDICAL SCHOOL · PI LIU, LAURA XIAOFEI-ROSE · 2012 to 2014
$90k
NHLBI NIH HHS R01 HL094499NIA NIH HHS F31 AG041598NIA NIH HHS F31AG041598
6 · The paper itself

Abstract

Pregnancy causes dramatic physiological changes in the expectant mother. The placenta, mostly foetal in origin, invades maternal uterine tissue early in pregnancy and unleashes a barrage of hormones and other factors. This foetal 'invasion' profoundly reprogrammes maternal physiology, affecting nearly every organ, including the heart and its metabolism. We briefly review here maternal systemic metabolic changes during pregnancy and cardiac metabolism in general. We then discuss changes in cardiac haemodynamic during pregnancy and review what is known about maternal cardiac metabolism during pregnancy. Lastly, we discuss cardiac diseases during pregnancy, including peripartum cardiomyopathy, and the potential contribution of aberrant cardiac metabolism to disease aetiology.

Indexed as

Blood CirculationFemaleHeart DiseasesHemodynamicsHumansMitochondriaPeripartum PeriodPlacentaPregnancyHeartMetabolismPeripartum cardiomyopathyPregnancy

Identifiers

PMID24448314
PMCPMC3941596
OpenAlexW2105532159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.