ArticleEmerging infectious diseases2014
Fungal endophthalmitis associated with compounded products.
Article in Emerging infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Pharmaceutical Compounding: a History, Regulatory Overview, and Systematic Review of Compounding Errors.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021Pooled it
- A five-year survey of dematiaceous fungi in a tropical hospital reveals potential opportunistic species.PloS one · 2014Trial
- Fungal Diseases Caused by Serious Contamination of Pharmaceuticals and Medical Devices, and Rapid Fungal Detection Using Nano-Diagnostic Tools: A Critical Review.Current microbiology · 2023Review
- A pseudo-outbreak ofFrontiers in cellular and infection microbiology · 2023Article
- Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020.Emerging infectious diseases · 2022Article
- Atypical Retinal Hemorrhages after Vitrectomy for Idiopathic Macular Hole: Possible Toxicity of Brilliant Blue G.Korean journal of ophthalmology : KJO · 2021Article
- Long-Term Outcomes of Macular Hole Repair with Triamcinolone Acetonide Visualization.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- U.S. Compounding Pharmacy-Related Outbreaks, 2001-2013: Public Health and Patient Safety Lessons Learned.Journal of patient safety · 2018Review
- Bomba Rice Conservation with a Natural Biofilm.ACS omega · 2018Article
- Emerging issues, challenges, and changing epidemiology of fungal disease outbreaks.The Lancet. Infectious diseases · 2017Review
- Endophthalmitis.Korean journal of ophthalmology : KJO · 2017Review
- Persistently Vitreous Culture-Positive Exogenous Fungal Endophthalmitis.American journal of ophthalmology · 2016Article
- Whole-Genome Sequencing to Determine Origin of Multinational Outbreak of Sarocladium kiliense Bloodstream Infections.Emerging infectious diseases · 2016Article
- Fusarium Endophthalmitis following Cataract Surgery: Successful Treatment with Intravitreal and Systemic Voriconazole.Case reports in ophthalmological medicine · 2016Article
- Macular laser photocoagulation with or without intravitreal triamcinolone pretreatment for diabetic macular edema: a result from five randomized controlled trials.International journal of ophthalmology · 2016Article
- Development of a Multilocus Sequence Typing System for Medically Relevant Bipolaris Species.Journal of clinical microbiology · 2015Article
- Investigating fungal outbreaks in the 21st century.PLoS pathogens · 2015Review
- Endophthalmitis: state of the art.Clinical ophthalmology (Auckland, N.Z.) · 2015Review
- Fungi associated with drug recalls and rare disease outbreaks.Journal of industrial microbiology & biotechnology · 2014Review
- Update on the prevention and treatment of endophthalmitis.Expert review of ophthalmology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungal endophthalmitis is a rare but serious infection. In March 2012, several cases of probable and laboratory-confirmed fungal endophthalmitis occurring after invasive ocular procedures were reported nationwide. We identified 47 cases in 9 states: 21 patients had been exposed to the intraocular dye Brilliant Blue G (BBG) during retinal surgery, and the other 26 had received an intravitreal injection containing triamcinolone acetonide. Both drugs were produced by Franck's Compounding Lab (Ocala, FL, USA). Fusarium incarnatum-equiseti species complex mold was identified in specimens from BBG-exposed case-patients and an unopened BBG vial. Bipolaris hawaiiensis mold was identified in specimens from triamcinolone-exposed case-patients. Exposure to either product was the only factor associated with case status. Of 40 case-patients for whom data were available, 39 (98%) lost vision. These concurrent outbreaks, associated with 1 compounding pharmacy, resulted in a product recall. Ensuring safety and integrity of compounded medications is critical for preventing further outbreaks associated with compounded products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.