Observational studyPediatrics2014
Cotinine in children admitted for asthma and readmission.
Observational study in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Serum cotinine cut-points for secondhand smoke exposure assessment in children under 5 years: A systemic review.PloS one · 2022Pooled it
- Predictors of repeated acute hospital attendance for asthma in children: A systematic review and meta-analysis.Pediatric pulmonology · 2018Pooled it
- Intervening With Smoking Parents of Inpatients to Reduce Exposure: The INSPIRE Randomized Controlled Trial.Academic pediatrics · 2022Trial
- Smoking Behaviors Among Tobacco-Using Parents of Hospitalized Children and Association With Child Cotinine Level.Hospital pediatrics · 2021Trial
- Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial.The Journal of pediatrics · 2018Trial
- Risk factors for asthma-related hospital and intensive care admissions in children, adolescents and adults: a cohort study using primary and secondary care data.BMJ open respiratory research · 2024Article
- Factors Influencing the Concentration of Exhaled Nitric Oxide (FeNO) in School Children Aged 8-9-Years-Old in Krakow, with High FeNO Values ≥ 20 ppb.Medicina (Kaunas, Lithuania) · 2022Article
- Hard to Reach or Just Not Enough? A Narrative Review of Inpatient Tobacco Cessation Programs in Pediatrics.International journal of environmental research and public health · 2021Review
- Genetic ancestry differences in pediatric asthma readmission are mediated by socioenvironmental factors.The Journal of allergy and clinical immunology · 2021Article
- Effect of Ambient Air Pollution on Hospital Readmissions among the Pediatric Asthma Patient Population in South Texas: A Case-Crossover Study.International journal of environmental research and public health · 2020Article
- Comparison of Liquid Chromatography Mass Spectrometry and Enzyme-Linked Immunosorbent Assay Methods to Measure Salivary Cotinine Levels in Ill Children.International journal of environmental research and public health · 2020Article
- Electronic Health Record Classification of Tobacco Smoke Exposure and Cotinine Levels in Hospitalized Pediatric Patients.Hospital pediatrics · 2019Article
- Tobacco Use Behaviors and Perceptions of Parental Smokers in the Emergency Department Setting.Tobacco use insights · 2019Article
- Assessing pediatric tobacco exposure using parent report: comparison with hair nicotine.Journal of exposure science & environmental epidemiology · 2018Article
- Active and passive smoking impacts on asthma with quantitative and temporal relations: A Korean Community Health Survey.Scientific reports · 2018Article
- Difficult vs. Severe Asthma: Definition and Limits of Asthma Control in the Pediatric Population.Frontiers in pediatrics · 2018Review
- Tobacco Smoke Exposure and Health-Care Utilization Among Children in the United States.American journal of health promotion : AJHP · 2018Article
- Secondhand Smoke Exposure and Pediatric Healthcare Visits and Hospitalizations.American journal of preventive medicine · 2017Article
- Secondhand smoke exposure, illness severity, and resource utilization in pediatric emergency department patients with respiratory illnesses.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017Article
- Characteristics of Pediatric Emergency Revisits After an Asthma-Related Hospitalization.Annals of emergency medicine · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveTo explore the relationship between tobacco smoke exposure (reported versus biomarker) and rates of readmission for children hospitalized for asthma.
methodsWe enrolled a prospective cohort of 774 children aged 1 to 16 years admitted for asthma or bronchodilator-responsive wheezing. The primary outcome was at least 1 asthma- or wheeze-related readmission within 1 year. Caregivers reported any tobacco exposure at home, in a secondary residence, or in the car. We measured serum and saliva cotinine levels with mass spectrometry. We used logistic regression to evaluate associations between tobacco exposure and readmissions.
resultsA total of 619 children had complete tobacco exposure data; 57% were African American and 76% had Medicaid. Seventeen percent of children were readmitted within 1 year. Tobacco exposure rates were 35.1%, 56.1%, and 79.6% by report, serum, and saliva measures, respectively. Caregiver report of any tobacco exposure was not associated with readmission (adjusted odds ratio: 1.18; 95% confidence interval: 0.79-1.89), but having detectable serum or salivary cotinine was associated with increased odds of readmission (adjusted odds ratio [95% confidence interval]: 1.59 [1.02-2.48] and 2.35 [1.22-4.55], respectively). Among children whose caregivers reported no tobacco exposure, 39.1% had detectable serum cotinine and 69.9% had detectable salivary cotinine. Of the children with reported exposure, 87.6% had detectable serum cotinine and 97.7% had detectable salivary cotinine.
conclusionsDetectable serum and salivary cotinine levels were common among children admitted for asthma and were associated with readmission, whereas caregiver report of tobacco exposure was not.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.