ReviewCurrent diabetes reports2014
Metabolic basis of ethnic differences in diabetes risk in overweight and obese youth.
Review in Current diabetes reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Knowledge mapping and bibliometric analysis of metabolic phenotypes in childhood and adolescent obesity: research hotspots and emerging trends from 2000 to 2026.Frontiers in public health · 2026Pooled it
- The triglyceride-glucose index as a biomarker of diabetic retinopathy: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Adipose Depot Changes and Associated Metabolic Risk in the Longitudinal Health Influences of Puberty Study.Pediatric obesity · 2026Trial
- Association between total, regional and organ fat and type 2 diabetes risk factors among Latino youth: A longitudinal study.Pediatric obesity · 2025Trial
- Trial
- Global, regional, and national trends and burden of diabetes mellitus type 2 among youth from 1990 to 2021: an analysis from the global burden of disease study 2021.Frontiers in endocrinology · 2025Article
- Increased circulating serpinB1 levels in children with overweight/obesity are associated with obesity-related parameters: a cross‑sectional study.BMC pediatrics · 2024Article
- Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes.Diabetology & metabolic syndrome · 2024Article
- Body Composition Changes Impact IsletJournal of lipids · 2024Article
- Ancestry-driven metabolite variation provides insights into disease states in admixed populations.Genome medicine · 2023Article
- Racial difference in the association between non-alcoholic fatty liver disease and incident type 2 diabetes: findings from the CARDIA study.Diabetologia · 2023Article
- Rapid Decline in β-Cell Function and Increasing Adiposity Are Associated With Conversion to Type 2 Diabetes in At-Risk Latino Youth.Diabetes · 2023Article
- Organ fat in Latino youth at risk for type 2 diabetes.Pediatric diabetes · 2022Article
- The Link between Obesity and Inflammatory Markers in the Development of Type 2 Diabetes in Men of Black African and White European Ethnicity.Nutrients · 2020Article
- Article
- Metabolic Disorders in HIV-Infected Adolescents Receiving Protease Inhibitors.BioMed research international · 2017Article
- Integrative network analysis reveals different pathophysiological mechanisms of insulin resistance among Caucasians and African Americans.BMC medical genomics · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The global pandemic of childhood obesity has led to increased risk for prediabetes and type 2 diabetes mellitus (T2DM). Studies have shown decreased insulin sensitivity and/or secretion with increasing adiposity and consistently observed greater risk for T2DM in obese, non-Caucasian youth. In the current review we describe recent advances in understanding how obesity and metabolic status in children and adolescents confers various risk profiles for T2DM among Latinos, African Americans, Caucasians, Asians, and Native Americans. These possible determinants include ectopic fat distribution, adipose tissue inflammation and fibrosis, and elevated plasma levels of nonesterified free fatty acids. Future work should aim to elucidate the ethnic-specific pathophysiology of T2DM in order to develop and implement appropriate prevention and treatment strategies based on different ethnic profiles of diabetes risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.