ReviewReports on progress in physics. Physical Society (Great Britain)2014
Noise in biology.
Review in Reports on progress in physics. Physical Society (Great Britain), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
155 citing papers in PubMed, 451 citations in OpenAlex.
- Structured Fluctuations and the Information Dynamics of Self-Maintenance in Growing Neural Cellular Automata.Entropy (Basel, Switzerland) · 2026Article
- Emergent phenotypic heterogeneity in synthetic cross-feeding consortia driven by heterogeneous metabolite distribution.National science review · 2026Article
- Article
- Passage-Dependent Size Distributions of Human-Derived Cells: Implications for Metabolic Assays.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Cell differentiation can underpin the reproducibility of morphogenesis.PLoS computational biology · 2026Article
- Assessment of dispersion metrics for estimating single-cell transcriptional variability.PLoS computational biology · 2026Article
- Noise-induced bimodality in self-regulated gene networks with nonlinear promoter transitions and fast dimerization.Journal of mathematical biology · 2026Article
- Small data, big challenges: Machine- and deep-learning strategies for data-limited drug discovery.Advanced drug delivery reviews · 2026Review
- Emergent universal long-range structure in random-organizing systems.Nature communications · 2026Article
- Integrating the Contrasting Perspectives Between the Constrained Disorder Principle and Deterministic Optical Nanoscopy: Enhancing Information Extraction from Imaging of Complex Systems.Bioengineering (Basel, Switzerland) · 2026Article
- From Decay to Rhythm: Coherent Biological Oscillators Require More Than Chemistry Alone.bioRxiv : the preprint server for biology · 2026Article
- Predicting Cardiovascular Events with Time-Lagged Inflammatory Dynamics: Stochastic Delay Modeling.Computational and structural biotechnology journal · 2026Article
- Rotating Gold Nanomotors for High-Resolution Mapping of Subcellular Nanomotions.Small methods · 2025Article
- A novel information-theoretic approach reveals loss of effective biomolecular communication in aging muscle cells.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- The constrained disorder principle emphasizes the importance of variability boundaries for systems to function effectively.Journal of medicine and life · 2025Article
- Towards a mathematical framework for modelling cell fate dynamics.Journal of mathematical biology · 2025Article
- Reconstructing noisy gene regulation dynamics using extrinsic-noise-driven neural stochastic differential equations.PLoS computational biology · 2025Article
- From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms.Development (Cambridge, England) · 2025Review
- Positioning of negative feedback loops within immune signaling pathways influences gene expression noise.bioRxiv : the preprint server for biology · 2025Article
- Review
95 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Noise permeates biology on all levels, from the most basic molecular, sub-cellular processes to the dynamics of tissues, organs, organisms and populations. The functional roles of noise in biological processes can vary greatly. Along with standard, entropy-increasing effects of producing random mutations, diversifying phenotypes in isogenic populations, limiting information capacity of signaling relays, it occasionally plays more surprising constructive roles by accelerating the pace of evolution, providing selective advantage in dynamic environments, enhancing intracellular transport of biomolecules and increasing information capacity of signaling pathways. This short review covers the recent progress in understanding mechanisms and effects of fluctuations in biological systems of different scales and the basic approaches to their mathematical modeling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.