Trial reportJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography2014
Relationship between echocardiographic and magnetic resonance derived measures of right ventricular size and function in patients with pulmonary hypertension.
Trial report in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2018Guideline
- Correlation of Echocardiographic Right Ventricular Functional Parameters with CMR-Derived Right Ventricular Ejection Fraction in Pulmonary Hypertension: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Assessment of Right Ventricular Adaptability to Pressure Overloading for Critical Therapeutic Decision-Making Processes.Journal of clinical medicine · 2026Review
- Pulmonary Hemodynamic Parameters Derived from 4D Flow MR Imaging Can Provide Sensitive Markers for Chronic Obstructive Pulmonary Disease (COPD) Patients with Right Ventricular Dysfunction.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Echocardiographic right ventricular remodeling after percutaneous atrial septal defect closure.International journal of cardiology. Congenital heart disease · 2023Article
- Evaluation of right ventricular performance in patients with postoperative congenital heart disease using Doppler tissue imaging and cardiopulmonary bypass indices: A prospective cohort study.Health science reports · 2022Article
- Role of Echocardiography in the Management of Patients with Advanced (Stage D) Heart Failure Related to Nonischemic Cardiomyopathy.Reviews in cardiovascular medicine · 2022Review
- The Challenge of Echocardiography in the Accurate Assessment of the Right Ventricle and Pulmonary Insufficiency.Arquivos brasileiros de cardiologia · 2021Article
- On the way to routine cardiac MRI at 7 Tesla - a pilot study on consecutive 84 examinations.PloS one · 2021Article
- Tripartite Assessment of Right Ventricular Systolic Function in Persistent Pulmonary Hypertension of the Newborn.Pediatric cardiology · 2020Article
- Right ventricular basal inflow and outflow tract diameters overestimate right ventricular size in subjects with sigmoid-shaped interventricular septum: a study using three-dimensional echocardiography.The international journal of cardiovascular imaging · 2019Observational
- Assessment of Right Ventricular Function in Pulmonary Hypertension with Multimodality Imaging.Journal of cardiovascular imaging · 2018Review
- Optimizing right ventricular focused four-chamber views using three-dimensional imaging, a comparative magnetic resonance based study.The international journal of cardiovascular imaging · 2018Article
- Right heart imaging in patients with heart failure: a tale of two ventricles.Current opinion in cardiology · 2016Review
- How best to assess right ventricular function by echocardiography.Cardiology in the young · 2015Review
- Survival benefits of warfarin in Korean patients with idiopathic pulmonary arterial hypertension.The Korean journal of internal medicine · 2015Article
- Assessment of Pulmonary Arterial Hypertension by Magnetic Resonance Imaging.Tomography (Ann Arbor, Mich.) · 2015Review
- Right Heart Score for Predicting Outcome in Idiopathic, Familial, or Drug- and Toxin-Associated Pulmonary Arterial Hypertension.JACC. Cardiovascular imaging · 2015Article
- Diagnosing and treating the failing right heart.Current opinion in cardiology · 2015Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTransthoracic echocardiographic (TTE) imaging is the mainstay of clinical practice for evaluating right ventricular (RV) size and function, but its accuracy in patients with pulmonary hypertension has not been well validated.
methodsMagnetic resonance imaging (MRI) and TTE images were retrospectively reviewed in 40 consecutive patients with pulmonary hypertension. RV and left ventricular volumes and ejection fractions were calculated using MRI. TTE areas and indices of RV ejection fraction (RVEF) were compared.
resultsThe average age was 42 ± 12 years, with a majority of women (85%). There was a wide range of mean pulmonary arterial pressures (27-81 mm Hg) and RV end-diastolic volumes (111-576 mL), RVEFs (8%-67 %), and left ventricular ejection fractions (26%-72%) by MRI. There was a strong association between TTE and MRI-derived parameters: RV end-diastolic area (by TTE imaging) and RV end-diastolic volume (by MRI), R(2) = 0.78 (P < .001); RV fractional area change by TTE imaging and RVEF by MRI, R(2) = 0.76 (P < .001); and tricuspid annular plane systolic excursion by TTE imaging and RVEF by MRI, R(2) = 0.64 (P < .001). By receiver operating characteristic curve analysis, an RV fractional area change < 25% provided excellent discrimination of moderate systolic dysfunction (RVEF < 35%), with an area under the curve of 0.97 (P < .001). An RV end-diastolic area index of 18 cm(2)/m(2) provided excellent discrimination for moderate RV enlargement (area under the curve, 0.89; P < .001).
conclusionsEchocardiographic estimates of RV volume (by RV end-diastolic area) and function (by RV fractional area change and tricuspid annular plane systolic excursion) offer good approximations of RV size and function in patients with pulmonary hypertension and allow the accurate discrimination of normal from abnormal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.