Trial reportPediatric obesity2015
Impact of maternal diet on neonatal anthropometry: a randomized controlled trial.
Trial report in Pediatric obesity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02916667 (Chrono Nutrition Intervention Program in Gestational Diabetes Mellitus), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chrono Nutrition Intervention Program in Gestational Diabetes Mellitus
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Animal models of maternal high fat diet exposure and effects on metabolism in offspring: a meta-regression analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2017Pooled it
- Dietary advice interventions in pregnancy for preventing gestational diabetes mellitus.The Cochrane database of systematic reviews · 2017Pooled it
- Trial
- Trial
- Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy.International journal of obesity (2005) · 2017Trial
- Trial
- Fetal metabolic influences of neonatal anthropometry and adiposity.BMC pediatrics · 2015Trial
- Maternal low glycaemic index diet, fat intake and postprandial glucose influences neonatal adiposity--secondary analysis from the ROLO study.Nutrition journal · 2014Trial
- Maternal Consumption of Fruits, Vegetables and Fruit Juices in Relation to Offspring Weight at 4 Years.Nutrients · 2026Observational
- Parental diet and offspring health: a role for the gut microbiome via epigenetics.Nature reviews. Gastroenterology & hepatology · 2025Review
- Macrosomia and Childhood Growth Trajectories From Birth to 10 Years of Age: Findings From the ROLO Longitudinal Birth Cohort Study.Journal of obesity · 2025Article
- The impact of macrosomia on cardiometabolic health in preteens: findings from the ROLO longitudinal birth cohort study.Nutrition & metabolism · 2023Article
- The Uterine Environment and Childhood Obesity Risk: Mechanisms and Predictions.Current nutrition reports · 2023Review
- Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening.Diagnostics (Basel, Switzerland) · 2023Review
- Childhood obesity and adverse cardiometabolic risk in large for gestational age infants and potential early preventive strategies: a narrative review.Pediatric research · 2022Review
- From conception to infancy - early risk factors for childhood obesity.Nature reviews. Endocrinology · 2019Review
- A reduction in sedentary behaviour in obese women during pregnancy reduces neonatal adiposity: the DALI randomised controlled trial.Diabetologia · 2019Article
- Article
- Article
- Adherence to the Mediterranean diet during pregnancy and offspring adiposity and cardiometabolic traits in childhood.Pediatric obesity · 2017Article
Corrections and comments
- Commented on by
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveLarge for gestational age infants are at increased risk of childhood obesity and maternal nutrition impacts birthweight. The aim of this study was to assess the impact of a maternal low glycaemic index (GI) diet on neonatal anthropometry.
methodsThe ROLO (Randomised Control Trial of Low Glycaemic Index Diet in Pregnancy) study was a randomized controlled trial to assess the impact of a low GI diet versus usual diet on birthweight. It took place in a tertiary maternity hospital in Ireland and women were randomized to receive either a low GI diet or no dietary intervention from early pregnancy to term. Two hundred sixty-five neonates had anthropometric measurements on day 1-2 of life, 126 in the intervention group and 139 in the control group. Measurements included birthweight, length and circumferences of the head, chest, abdominal, thigh and mid-upper arm. A subgroup of 219 (82%) neonates also had skin-fold measurements.
resultsNeonates whose mothers had a low GI diet in pregnancy had lower thigh circumference (15.9 ± 1.7 cm vs. 16.6 ± 1.5 cm, P = 0.04). There was no difference between the intervention and control groups in head, chest abdominal or mid-upper arm circumferences. No difference was noted between the two groups for any skin-fold measurements (subscapular, thigh, biceps and triceps).
conclusionNeonatal thigh circumference was altered by maternal low GI diet in pregnancy. These findings suggest that maternal low GI diet is safe in pregnancy and may positively impact infant adiposity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.