ReviewStem cells translational medicine2014
Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features.
Review in Stem cells translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Artificial activation of clinically failed human oocytes enables euploid blastocyst formation.Journal of assisted reproduction and genetics · 2026Article
- Effects of Embryo Production Method and Culture Medium on Embryonic Development in Red-Rumped Agouti.Cell biology international · 2025Article
- Characteristics of Parthenogenetic Stem Cells and Their Potential Treatment Strategy for Central Nervous System Diseases.Neuropsychiatric disease and treatment · 2025Review
- Mitochondria: emerging therapeutic strategies for oocyte rescue.Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- Induced Pluripotent Stem Cells for Treatment of Alzheimer's and Parkinson's Diseases.Biomedicines · 2022Review
- Blastocyst development after fertilization with in vitro spermatids derived from nonhuman primate embryonic stem cells.F&S science · 2021Article
- Stem cells and reproduction.BMB reports · 2019Review
- Human parthenogenetic neural stem cell grafts promote multiple regenerative processes in a traumatic brain injury model.Theranostics · 2019Article
- Mitochondrial replacement therapy and assisted reproductive technology: A paradigm shift toward treatment of genetic diseases in gametes or in early embryos.Reproductive medicine and biology · 2018Review
- 3D-cultured adipose tissue-derived stem cells inhibit liver cancer cell migration and invasion through suppressing epithelial-mesenchymal transition.International journal of molecular medicine · 2018Article
- Myocardial Tissue Engineering for Regenerative Applications.Current cardiology reports · 2017Review
- Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease.Scientific reports · 2016Article
- Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes.Nature communications · 2016Article
- Human pluripotent stem cells: Prospects and challenges as a source of cardiomyocytes for in vitro modeling and cell-based cardiac repair.Advanced drug delivery reviews · 2016Review
- Parthenogenesis and Human Assisted Reproduction.Stem cells international · 2016Review
- Chromosomal instability in mammalian pre-implantation embryos: potential causes, detection methods, and clinical consequences.Cell and tissue research · 2016Review
- Human Parthenogenetic Embryonic Stem Cell-Derived Neural Stem Cells Express HLA-G and Show Unique Resistance to NK Cell-Mediated Killing.Molecular medicine (Cambridge, Mass.) · 2015Article
- Mitochondrial replacement therapy in reproductive medicine.Trends in molecular medicine · 2015Review
- Article
- Concise review: animal substance-free human embryonic stem cells aiming at clinical applications.Stem cells translational medicine · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Embryonic stem cells (ESCs) have the potential to provide unlimited cells and tissues for regenerative medicine. ESCs derived from fertilized embryos, however, will most likely be rejected by a patient's immune system unless appropriately immunomatched. Pluripotent stem cells (PSCs) genetically identical to a patient can now be established by reprogramming of somatic cells. However, practical applications of PSCs for personalized therapies are projected to be unfeasible because of the enormous cost and time required to produce clinical-grade cells for each patient. ESCs derived from parthenogenetic embryos (pESCs) that are homozygous for human leukocyte antigens may serve as an attractive alternative for immunomatched therapies for a large population of patients. In this study, we describe the biology and genetic nature of mammalian parthenogenesis and review potential advantages and limitations of pESCs for cell-based therapies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.