ArticleSurgical endoscopy2014
Endoscopic resection of sporadic duodenal adenomas: comparison of endoscopic mucosal resection (EMR) with hybrid endoscopic submucosal dissection (ESD) techniques and the risks of late delayed bleeding.
Article in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Comparison of vonoprazan and proton pump inhibitors for the treatment of gastric endoscopic submucosal dissection-induced ulcer: an updated systematic review and meta-analysis.BMC gastroenterology · 2024Pooled it
- Trial
- Comparative efficacy and safety of hybrid versus conventional endoscopic submucosal dissection for non-ampullary duodenal submucosal tumors.Surgical endoscopy · 2026Article
- Safety and efficacy of endoscopic papillectomy for duodenal papillary adenomas: A single-center retrospective study.World journal of gastrointestinal surgery · 2026Article
- Usefulness of the S-O clip for duodenal endoscopic submucosal dissection: a propensity score-matched study.Clinical endoscopy · 2023Article
- Effectiveness and safety of endoscopic resection for duodenal gastrointestinal stromal tumors: A single center analysis.World journal of gastrointestinal endoscopy · 2022Article
- Sporadic non-ampullary duodenal adenomas: efficacy and outcomes of endoscopic resection.Surgical endoscopy · 2022Article
- Injectable Self-Healing Adhesive pH-Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing.Nano-micro letters · 2021Article
- Endoscopic mucosal resection of sporadic duodenal nonampullary adenoma: outcomes of 130 patients with a long-term follow up in two tertiary French centers.Annals of gastroenterology · 2021Article
- Endoscopic mucosal resectionWorld journal of gastrointestinal oncology · 2020Article
- Long-term outcomes of endoscopic resection for non-ampullary duodenal epithelial tumors: A single-center experience.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Observational
- Novel endoscopic treatment strategy for early esophageal cancer in cirrhotic patients with esophageal varices.Oncology letters · 2019Article
- The flat and immobile villi sign: a novel approach in identifying duodenal adenomas.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2019Article
- Comparative analysis of ESD versus EMR in a large European series of non-ampullary superficial duodenal tumors.Endoscopy international open · 2018Article
- ESD versus EMR in non-ampullary superficial duodenal tumors: a systematic review and meta-analysis.Endoscopy international open · 2018Review
- Endoscopic and surgical management of nonampullary duodenal neoplasms.Surgical endoscopy · 2018Article
- Real-life evaluation of the safety, efficacy and therapeutic outcomes of endoscopic submucosal dissection in a Western tertiary centre.United European gastroenterology journal · 2018Article
- Do we know enough?-sporadic non-ampullary duodenal neoplasms (SNADNs).Translational gastroenterology and hepatology · 2018Article
- Safety of endoscopic resection for duodenal subepithelial lesions with wound closure using clips and an endoloop: an analysis of 68 cases.Surgical endoscopy · 2017Article
- Performance measures for upper gastrointestinal endoscopy: A European Society of Gastrointestinal Endoscopy quality improvement initiative.United European gastroenterology journal · 2016Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic resection (ER) of sporadic duodenal adenomas (SDAs) is an alternative treatment strategy to surgical excision but carries substantial risks of bleeding. Endoscopic submucosal dissection (ESD) of SDAs has a high rate of perforation. This study aimed to examine the outcome for ER of SDAs in two large UK centers, both using a novel hybrid endoscopic mucosal resection (EMR) with ESD.
methodsProspective endoscopy databases of ER cases were examined for the period January 2005 to December 2012. Records were analyzed for patient demographics, lesion size and morphology, staging investigations, procedural technique, outcomes, histology, complications, and follow-up assessments.
resultsThe study included 34 patients. The mean adenoma size was 25 mm. Of the 34 cases, 21 (62 %) were managed by the traditional snare EMR technique, 12 (35 %) by the hybrid EMR-ESD technique, and 1 by full en bloc ESD. Successful resection was achieved in 33 (97 %) of the 34 cases. En bloc resection and recurrence rates did not differ significantly between the cases treated by EMR and those treated by hybrid EMR-ESD. Three episodes of significant delayed bleeding occurred 1-18 days after the procedure. No perforations or deaths occurred. The risk of delayed bleeding was higher for the lesions 30 mm in diameter or larger than for the lesions smaller than 30 mm (33% vs. 0 %; p = 0.003). The risk of delayed bleeding was not related to the ER technique used (EMR, 9.5 %; ESD/hybrid, 7.7 %; p = 0.855).
conclusionsEndoscopic resection is an effective treatment for SDAs and can avoid the need for open surgery. This is the first series to report the use of a hybrid EMR-ESD technique for the treatment of SDAs in a Western setting. However, this technique did not confer any major outcome benefits over EMR. The risk of delayed bleeding is substantial, and bleeding may occur up to 18 days after the procedure. The risk of delayed bleeding was increased with lesions larger than 30 mm but was not influenced by the endoscopic technique.
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