Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2014
Microfracture technique versus osteochondral autologous transplantation mosaicplasty in patients with articular chondral lesions of the knee: a prospective randomized trial with long-term follow-up.
Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Surgery for early structural osteoarthritis of the hip and knee: the SCORE evidence synthesis and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Pooled it
- Microfracture for cartilage repair in the knee: a systematic review of the contemporary literature.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- Changing trends in the use of cartilage restoration techniques for the patellofemoral joint: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Pooled it
- A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up.Journal of orthopaedic surgery and research · 2025Trial
- Norwegican Cartilage Project - a study protocol for a double-blinded randomized controlled trial comparing arthroscopic microfracture with arthroscopic debridement in focal cartilage defects in the knee.BMC musculoskeletal disorders · 2016Trial
- Focal cartilage defects in the knee - a randomized controlled trial comparing autologous chondrocyte implantation with arthroscopic debridement.BMC musculoskeletal disorders · 2016Trial
- Treatment Options for Focal Cartilage Lesions of the Knee.Deutsches Arzteblatt international · 2026Review
- A Prospective Clinical and Magnetic Resonance Imaging-Based Follow-up Beyond 10 Years After Arthroscopic Matrix-Induced Autologous Chondrocyte Implantation.The American journal of sports medicine · 2026Article
- Comparative effectiveness of osteochondral restoration, cell-based regeneration and cell-free implants for knee chondral defects: a systematic review.BMJ open sport & exercise medicine · 2026Article
- Midterm Outcomes of Primary Osteochondral Autograft Transfer for Symptomatic Chondral Defects of the Knee.Orthopaedic journal of sports medicine · 2026Article
- Stem cell-based cartilage regeneration: Biological strategies, engineering innovations, and clinical translation.World journal of stem cells · 2025Review
- Autologous Osteochondral Transfer Demonstrates Satisfactory Clinical Outcomes and Durable Cartilage Properties: A Mean 4-Year Follow-up Using Quantitative MRI.Orthopaedic journal of sports medicine · 2025Article
- Functional outcome after arthroscopic mosaicplasty for localised osteochondral defects in the knee.Medical journal, Armed Forces India · 2025Article
- Acellular Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions of the Knee: A Minimum 5-Year Follow-Up Study.Cartilage · 2024Article
- Comparison of the bioactivity and apoptotic responses of hyaline cartilage chondrocytes and fibrocartilage chondrocytes obtained by bone marrow stimulation in rats.Acta orthopaedica et traumatologica turcica · 2024Article
- Does progress in microfracture techniques necessarily translate into clinical effectiveness?World journal of orthopedics · 2024Article
- 10-Year Prospective Clinical and Radiological Evaluation After Matrix-Induced Autologous Chondrocyte Implantation and Comparison of Tibiofemoral and Patellofemoral Graft Outcomes.The American journal of sports medicine · 2024Article
- Knee Cartilage Lesion Management-Current Trends in Clinical Practice.Journal of clinical medicine · 2023Review
- Correlation analysis of cartilage wear with biochemical composition, viscoelastic properties and friction.Journal of the mechanical behavior of biomedical materials · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare long-term functional and radiological outcome following microfracture technique (MF) versus osteochondral autologous transplantation (OAT) mosaicplasty for treating focal chondral lesions of the knee.
methodsTwenty-five patients (mean age 32.3 years, SD 7.7) with a full-thickness (International Cartilage Repair Society grade 3 or 4) chondral lesion of the articulating surface of the femur were randomized to either MF (n = 11) or OAT mosaicplasty (n = 14). At a median follow-up of 9.8 years (range 4.9-11.4), the patients were evaluated using Lysholm score (n = 25), Knee Injury and Osteoarthritis Outcome Score (KOOS, n = 25), isokinetic quadriceps measurement and hamstring strength measurement (n = 22) and standing radiographs (n = 23).
resultsThere were no significant differences in Lysholm score, KOOS, isokinetic muscle strength or radiographic osteoarthritis between MF-treated patients and OAT mosaicplasty-treated patients at follow-up. Mean Lysholm score at follow-up was 69.7 [95% confidence interval (CI), 55.1-84.4] for the MF group and 62.6 (95% CI, 52.6-72.6) for the OAT mosaicplasty group.
conclusionAt long-term follow-up, there were no significant differences between patients treated with MF and patients treated with OAT mosaicplasty in patient-reported outcomes, muscle strength or radiological outcome. LEVEL OF EVIDENCE: Therapeutic study, Level II.
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