ArticleEuropean journal of histochemistry : EJH2013
An immunohistochemical study of matrix proteins in the craniofacial cartilage in midterm human fetuses.
Article in European journal of histochemistry : EJH, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Matrix components in the developing bones and cartilage of embryonic chick skulls: an in situ hybridization study.Anatomical science international · 2026Article
- Development and growth of the human fetal sacroiliac joint revisited: a comparison with the temporomandibular joint.Anatomy & cell biology · 2023Article
- Main and Minor Types of Collagens in the Articular Cartilage: The Role of Collagens in Repair Tissue Evaluation in Chondral Defects.International journal of molecular sciences · 2021Review
- Article
- Expression, localization and synthesis of small leucine-rich proteoglycans in developing mouse molar tooth germ.European journal of histochemistry : EJH · 2020Article
- Diverse Fate of an Enigmatic Structure: 200 Years of Meckel's Cartilage.Frontiers in cell and developmental biology · 2020Review
- Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-1.Scientific reports · 2018Article
- Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia.European journal of histochemistry : EJH · 2017Article
- Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles.International journal of molecular sciences · 2016Article
- Development of synovial membrane in the temporomandibular joint of the human fetus.European journal of histochemistry : EJH · 2015Article
- An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage.European journal of histochemistry : EJH · 2015Article
- Candidate Gene Analyses of Skeletal Variation in Malocclusion.Journal of dental research · 2015Article
- Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal.European journal of histochemistry : EJH · 2014Article
- Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study.European journal of histochemistry : EJH · 2014Article
- Histochemistry as a unique approach for investigating normal and osteoarthritic cartilage.European journal of histochemistry : EJH · 2014Review
- Histochemistry as an irreplaceable approach for investigating functional cytology and histology.European journal of histochemistry : EJH · 2013Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunohistochemical localization of collagen types I, II, and X, aggrecan, versican, dentin matrix protein (DMP)-1, martix extracellular phosphoprotein (MEPE) were performed for Meckel's cartilage, cranial base cartilage, and mandibular condylar cartilage in human midterm fetuses; staining patterns within the condylar cartilage were compared to those within other cartilaginous structures. Mandibular condylar cartilage contained aggrecan; it also had more type I collagen and a thicker hypertrophic cell layer than the other two types of cartilage; these three characteristics are similar to those of the secondary cartilage of rodents. MEPE immunoreactivity was first evident in the cartilage matrix of all types of cartilage in the human fetuses and in Meckel's cartilage of mice and rats. MEPE immunoreactivity was enhanced in the deep layer of the hypertrophic cell layer and in the cartilaginous core of the bone trabeculae in the primary spongiosa. These results indicated that MEPE is a component of cartilage matrix and may be involved in cartilage mineralization. DMP-1 immunoreactivity first became evident in human bone lacunae walls and canaliculi; this pattern of expression was comparable to the pattern seen in rodents. In addition, chondroid bone was evident in the mandibular (glenoid) fossa of the temporal bone, and it had aggrecan, collagen types I and X, MEPE, and DMP-1 immunoreactivity; these findings indicated that chondroid bone in this region has phenotypic expression indicative of both hypertrophic chondrocytes and osteocytes.
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