ArticleBMJ open2014
Burn injury, gender and cancer risk: population-based cohort study using data from Scotland and Western Australia.
Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Neuropathic agents in the management of pruritus in burn injuries: a systematic review and meta-analysis.Trauma surgery & acute care open · 2021Pooled it
- Does exercise influence burn-induced inflammation: A cross-over randomised controlled feasibility trial.PloS one · 2022Trial
- Targeting Immune Dysregulation After Burn Injury for Improved Healing and Outcomes.Biomolecules · 2026Review
- Nonsevere Burn Induces a Prolonged Systemic Metabolic Phenotype Indicative of a Persistent Inflammatory Response Postinjury.Journal of proteome research · 2024Article
- Parental Stress and Child Quality of Life after Pediatric Burn.European burn journal · 2024Article
- The impact of burn injury on the central nervous system.Burns & trauma · 2024Review
- Review
- Current understanding of the chronic stress response to burn injury from human studies.Burns & trauma · 2023Review
- [Burn injury should be considered as a chronic disease].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells.Burns & trauma · 2022Article
- Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response.Frontiers in immunology · 2020Article
- Understanding acute burn injury as a chronic disease.Burns & trauma · 2019Review
- The accuracy of burn diagnosis codes in health administrative data: A validation study.Burns : journal of the International Society for Burn Injuries · 2017Article
- Burn Injury Leads to Increased Long-Term Susceptibility to Respiratory Infection in both Mouse Models and Population Studies.PloS one · 2017Article
- Long-term musculoskeletal morbidity after adult burn injury: a population-based cohort study.BMJ open · 2015Article
- The Immune Response to Skin Trauma Is Dependent on the Etiology of Injury in a Mouse Model of Burn and Excision.The Journal of investigative dermatology · 2015Article
- Long-term mortality among older adults with burn injury: a population-based study in Australia.Bulletin of the World Health Organization · 2015Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the risk of cancer and potential gender effects in persons hospitalised with burn injury.
designPopulation-based retrospective cohort study using record-linkage systems in Scotland and Western Australia.
participantsRecords of 37 890 and 23 450 persons admitted with a burn injury in Scotland and Western Australia, respectively, from 1983 to 2008. Deidentified extraction of all linked hospital morbidity records, mortality and cancer records were provided by the Information Service Division Scotland and the Western Australian Data Linkage Service.
main outcome measuresTotal and gender-specific number of observed and expected cases of total ('all sites') and site-specific cancers and standardised incidence ratios (SIRs).
resultsFrom 1983 to 2008, for female burn survivors, there was a greater number of observed versus expected notifications of total cancer with 1011 (SIR, 95% CI 1.3, 1.2 to 1.4) and 244 (SIR, 95% CI 1.12, 1.05 to 1.30), respectively, for Scotland and Western Australia. No statistically significant difference in total cancer risk was found for males. Significant excesses in observed cancers among burn survivors (combined gender) in Scotland and Western Australian were found for buccal cavity, liver, larynx and respiratory tract and for cancers of the female genital tract.
conclusionsResults from the Scotland data confirmed the increased risk of total ('all sites') cancer previously observed among female burn survivors in Western Australia. The gender dimorphism observed in this study may be related to the role of gender in the immune response to burn injury. More research is required to understand the underlying mechanism(s) that may link burn injury with an increased risk of some cancers.
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