ArticleDrug and alcohol dependence2014
Estimating the causal effects of cumulative treatment episodes for adolescents using marginal structural models and inverse probability of treatment weighting.
Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
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- The Longitudinal Association of Cumulative Depression With Cannabis Use Disorder Among Young Adults.Journal of studies on alcohol and drugs · 2025Article
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- Seven years of the transcarotid artery revascularization surveillance project, comparison to transfemoral stenting and endarterectomy.Journal of vascular surgery · 2024Article
- A tutorial comparing different covariate balancing methods with an application evaluating the causal effects of substance use treatment programs for adolescents.Health services & outcomes research methodology · 2023Article
- Comparative effectiveness of individual versus family-based substance use treatment on adolescent self-injurious thoughts and behaviors.Journal of substance abuse treatment · 2022Article
- Association Between Enrollment in Maryland's Behavioral Health Homes and Use of Outpatient Mental Health Services.Psychiatric services (Washington, D.C.) · 2021Article
- Nonparametric Estimation of Population Average Dose-Response Curves using Entropy Balancing Weights for Continuous Exposures.Health services & outcomes research methodology · 2021Article
- Expanding outcomes when considering the relative effectiveness of two evidence-based outpatient treatment programs for adolescents.Journal of substance abuse treatment · 2020Observational
- Effects of Maryland's Affordable Care Act Medicaid Health Home Waiver on Quality of Cardiovascular Care Among People with Serious Mental Illness.Journal of general internal medicine · 2020Article
- HPV vaccine status and sexual behavior among young sexually-active women in the US: evidence from the National Health and Nutrition Examination Survey, 2007-2014.Health economics, policy, and law · 2020Article
- Modelling Long-Term Joint Trajectories of Heroin Use and Treatment Utilisation: Findings from the Australian Treatment Outcome Study.EClinicalMedicine · 2019Article
- Comparison of Endovascular Stent Grafts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries.Annals of vascular surgery · 2018Article
- Examination of cumulative effects of early adolescent depression on cannabis and alcohol use disorder in late adolescence in a community-based cohort.Addiction (Abingdon, England) · 2017Article
- Confounding in longitudinal studies in addiction treatment research.Addiction research & theory · 2017Article
- Daily stressors as antecedents, correlates, and consequences of alcohol and drug use and cravings in community-based offenders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017Article
- The effects of the Maryland Medicaid Health Home Waiver on Emergency Department and inpatient utilization among individuals with serious mental illness.General hospital psychiatryArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundSubstance use treatment is rarely a one-time event for individuals with substance use disorders. Sustained reductions in substance use and its related symptoms may result from multiple treatment episodes.
methodsWe use a marginal structural model with inverse-probability-of-treatment weighting to estimate the causal effects of cumulative treatment experiences over a period of 9 months on drug use at the end of 1-year among 2870 adolescents receiving care in community-based treatment settings. During the 9 months, adolescents move in and out of outpatient and residential treatment with periods where they only receive biological drug screening (BDS) or no treatment at all. The use of inverse-probability-of-treatment weighting reduces confounding bias due to observed baseline and time-varying measures over the course of follow-up; weights were estimated using generalized boosted models.
resultsEach additional period of treatment (representing at least one day, 1 session, or 1 BDS during the 90 day period between follow-up visits) yielded reductions in average substance use frequency at 1-year relative to no treatment during the 90-day period. For residential treatment it was a 16% decrease (95% CI=-27%, -7%), for outpatient treatment it was a 9% decrease (95% CI=-18%, -0%), and for BDS (with no additional outpatient or residential treatment) it was an 11% decrease (95% CI=-20%, -3%).
conclusionsUsing robust statistical methods, we find promising (albeit preliminary) evidence that additional periods of outpatient and residential treatment, as well as biological drug screening, lead to reductions in substance use outcomes at one year.
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