Evidence map›Paper›PMID 24439948›Full record

ArticleWomen's health issues : official publication of the Jacobs Institute of Women's Health

Gender differences in cardiovascular risk factors in incident diabetes.

Emily B Schroeder, Elizabeth A Bayliss, Stacie L Daugherty, John F Steiner

Open access · greenAbstract read
In one paragraph

Article in Women's health issues : official publication of the Jacobs Institute of Women's Health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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  12. Sex differences in type 2 diabetes: focus on disease course and outcomes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emily B SchroederInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado; Department of Medicine, University of Colorado Denver, Aurora, Colorado. Electronic address: emily.x.schroeder@kp.org.
Elizabeth A BaylissInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado; Department of Family Medicine, University of Colorado Aurora, Denver, Colorado.
Stacie L DaughertyInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado; Department of Medicine, University of Colorado Denver, Aurora, Colorado.
John F SteinerInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado; Department of Medicine, University of Colorado Denver, Aurora, Colorado.
Kaiser Permanente · USUniversity of Colorado Denver · US

Funding

Multi-institutional Consortium for CER in Diabetes Treatment and PreventionR01HS019859 · AHRQ · KAISER FOUNDATION RESEARCH INSTITUTE · PI STEINER, JOHN F · 2010 to 2010
$8.9M
Gender Disparities in Invasive CVD Procedure Use: the Role of Provider BiasK08HL103776 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DAUGHERTY, STACIE LUTHER · 2010 to 2014
$657k
The effect of incident comorbidities on guideline-concordant chronic disease careR21HS017627 · AHRQ · KAISER FOUNDATION RESEARCH INSTITUTE · PI BAYLISS, ELIZABETH A · 2008 to 2009
$307k
AHRQ HHS 1R01 HS019859-01AHRQ HHS 1 R21 HS017627-01AHRQ HHS R01 HS019859AHRQ HHS R21 HS017627NHLBI NIH HHS K08 HL103776NHLBI NIH HHS K08 HL103776-02NIDDK NIH HHS L30 DK093053
6 · The paper itself

Abstract

backgroundCardiovascular disease is a major cause of morbidity and mortality for women and men with diabetes. Previous cross-sectional studies of prevalent diabetes have found that women are less likely to meet American Diabetes Association (ADA) and American Heart Association guidelines for control of cardiovascular risk factors (hemoglobin A1c, low-density lipoprotein [LDL] cholesterol, and blood pressure), but have not studied the critical period immediately after diagnosis.

methodsTo assess gender differences in cardiovascular risk factors at the time of diabetes diagnosis (baseline) and 1 year later (follow-up), we conducted a retrospective cohort study of 6,547 individuals with incident diabetes in an integrated care delivery system. We assessed mean cardiovascular risk factor values by gender and adjusted odds ratios of attaining ADA goals.

findingsCompared with men, at baseline women had lower hemoglobin A1c (7.9% vs. 8.2%; p < .001), higher LDL cholesterol (118.9 vs. 111.5 mg/dL; p < .001), higher systolic blood pressure (131.9 vs. 130.5 mmHg; p < .001), and lower diastolic blood pressure (79.1 vs. 79.7 mmHg; p = .006). At follow-up, the hemoglobin A1c gender gap had closed (6.9% vs. 6.9%; p = .39), and the gender gaps had decreased for blood pressure (129.8/77.0 vs. 128.9/77.6; p = .009) and LDL cholesterol (104.0 vs. 98.2 mg/dL; p < .001). These associations varied by age. Adjusted odds ratios showed similar relationships.

conclusionsIn this cohort of individuals with incident diabetes, men and women had important differences in risk factor control at the time of diabetes diagnosis. These differences varied by age and decreased over time.

Indexed as

AdultAgedAge FactorsAntihypertensive AgentsBlood PressureCardiovascular DiseasesCholesterol, LDLDelivery of Health Care, IntegratedDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinHumansIncidenceInsulinMaleAntihypertensive AgentsCholesterol, LDLGlycated HemoglobinInsulin

Identifiers

PMID24439948
PMCPMC3932744
OpenAlexW2090299968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.