Evidence map›Paper›PMID 24439845›Full record

ArticleJournal of pain and symptom management2014

Fatigue in family caregivers of adult intensive care unit survivors.

JiYeon Choi, Judith A Tate, Leslie A Hoffman, Richard Schulz, Dianxu Ren, Michael P Donahoe, Barbara A Given, Paula R Sherwood

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of pain and symptom management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05827354 (Incidence and Factors Associated to The Development of Post-Intensive Care Syndrome Among Family Members of Intensive Care Unit Survivors), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05827354 unknown statusnot on this mapstarted 2023, after this paper: background citation

Incidence and Factors Associated to The Development of Post-Intensive Care Syndrome Among Family Members of Intensive Care Unit Survivors: A Longitudinal Exploratory Study

TypeobservationalSponsorPontificia Universidad Catolica de ChileRan2023 to 2025Enrolled175ConditionsPost Intensive Care Syndrome, Family Members, Caregiver Burden, Critical Illness
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
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  9. Integrating Perspectives on Family Caregiving After Critical Illness: A Qualitative Content Analysis.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

JiYeon ChoiDepartment of Acute & Tertiary Care, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA. Electronic address: jic11@pitt.edu.
Judith A TateDepartment of Acute & Tertiary Care, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA.
Leslie A HoffmanDepartment of Acute & Tertiary Care, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Richard SchulzUniversity Center for Social and Urban Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Dianxu RenDepartment of Health & Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA; Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
Michael P DonahoeDivision of Pulmonary, Allergy & Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Barbara A GivenCollege of Nursing, The Michigan State University, East Lansing, Michigan, USA.
Paula R SherwoodDepartment of Acute & Tertiary Care, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA; Department of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · USMichigan State University · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F · 2011 to 2015
$8.3M
CLINICAL RESEARCH TRAINING IN LATE-LIFE MOOD DISORDERST32MH019986 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Carmen Andreescu · 1997 to 2026
$6.9M
Technology Research in Chronic & Critical IllnessT32NR008857 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Young Ji Lee · 2005 to 2026
$4.0M
Caregivers of Prolonged Mechanical Ventilation: Mind-Body Interaction ModelF32NR011271 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHOI, JIYEON · 2009 to 2010
$83k
NCATS NIH HHS UL1 TR000005NIMH NIH HHS P30 MH090333NIMH NIH HHS T32 MH019986NIMH NIH HHS T32 MH19986NINR NIH HHS F32 NR011271NINR NIH HHS T32 NR008857NINR NIH HHS T32NR008857
6 · The paper itself

Abstract

contextFamily caregivers are a vital resource in the recovery of intensive care unit (ICU) survivors. Of concern, the stress associated with this role can negatively affect caregiver health. Fatigue, an important health indicator, has been identified as a predictor of various illnesses, greater use of health services, and early mortality. Examining the impact of fatigue on caregivers' physical health can assist in identifying critical time points and potential targets for intervention.

objectivesTo describe self-reported fatigue in caregivers of ICU survivors from patients' ICU admission to ≤ 2 weeks, two- and four-months post-ICU discharge.

methodsPatient-caregiver pairs were enrolled from a medical ICU. Caregiver fatigue was measured using the Short-Form 36 Health Survey Vitality subscale (SF-36 Vitality). Caregiver psychobehavioral stress responses included depressive symptoms, burden, health risk behaviors, and sleep quality. Patient data included self-reported physical symptoms and disposition (home vs. institution).

resultsForty-seven patient-caregiver pairs were initially enrolled. Clinically significant fatigue (SF-36 Vitality ≤ 45) was reported by 43%-53% of caregivers across the time points, and these caregivers reported worse scores in measures of depressive symptoms, burden, health risk behaviors and sleep quality, and patients' symptom burden. In 26 caregivers with data for all time points (55% of the total sample), SF-36 Vitality scores showed trends of improvement when the patient returned home and greater impairment when institutionalization continued.

conclusionIn caregivers of ICU survivors, fatigue is common and potentially linked with poor psychobehavioral responses. Worsening fatigue was associated with greater symptom distress and long-term patient institutionalization.

Indexed as

Intensive Care UnitsSurvivorsCaregiversFamilyFatigueFemaleHumansLongitudinal StudiesMaleMiddle AgedPatient DischargeSeverity of Illness IndexStress, PsychologicalTertiary Care CentersTime Factorsburdencaregiver healthdepressive symptomsfamily caregiversfatigueIntensive care unitlong-term outcomes

Identifiers

PMID24439845
PMCPMC4101057
OpenAlexW1975560977

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.