Evidence map›Paper›PMID 24439804›Full record

ReviewCurrent topics in developmental biology2014

Epithelial stem cells in adult skin.

Ana Mafalda Baptista Tadeu, Valerie Horsley

Open access · greenAbstract readReview
In one paragraph

Review in Current topics in developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
62.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  6. Review
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  9. Article
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  13. Article
  14. E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  15. Article
  16. Article
  17. Stem Cells in the Cornea.Progress in molecular biology and translational science · 2015
    Review
  18. Article
  19. Developing stratified epithelia: lessons from the epidermis and thymus.Wiley interdisciplinary reviews. Developmental biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ana Mafalda Baptista TadeuDepartment of Molecular, Cell and Developmental Biology, Yale University, New Haven, Connecticut, USA.
Valerie HorsleyDepartment of Molecular, Cell and Developmental Biology, Yale University, New Haven, Connecticut, USA. Electronic address: valerie.horsley@yale.edu.
Yale University · US

Funding

Extrinsic Regulation of Epidermal HomeostatasisR01AR060295 · NIAMS · YALE UNIVERSITY · PI HORSLEY, VALERIE · 2011 to 2016
$2.2M
Extrinsic Regulation that Regulate Skin HomeostasisR56AR060295 · NIAMS · YALE UNIVERSITY · PI HORSLEY, VALERIE · 2018 to 2018
$481k
NIAMS NIH HHS AR060295NIAMS NIH HHS R01 AR060295NIAMS NIH HHS R56 AR060295
6 · The paper itself

Abstract

The skin is the first line of defense against dehydration and external environmental aggressions. It constantly renews itself throughout adult life mainly due to the activity of tissue-specific stem cells. In this review, we discuss fundamental characteristics of different stem cell populations within the skin and how they are able to contribute to normal skin homeostasis. We also examine the most recent results regarding the cell-intrinsic and -extrinsic components of the stem cell niche within the adult skin epithelium. Finally, we address the recent efforts to understand how abnormal regulation of stem cell activity contributes to the initiation and progression of skin-associated cancers.

Indexed as

Models, BiologicalAdultBasal Cell CarcinomaCellular MicroenvironmentEpithelial CellsExocrine GlandsHumansSkinStem CellsEpidermisHair follicleMerkel cellSebaceous glandStem cellsSweat gland

Identifiers

PMID24439804
PMCPMC5595246
OpenAlexW86524283

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.