Evidence map›Paper›PMID 24439344›Full record

Trial reportAmerican journal of preventive medicine2014

Temporal shifts in cardiovascular risk factor distribution.

Gráinne H Long, Rebecca K Simmons, Margareta Norberg, Patrik Wennberg, Bernt Lindahl, Olov Rolandsson, Simon J Griffin, Lars Weinehall

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in American journal of preventive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gráinne H LongMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Rebecca K SimmonsMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Margareta NorbergDepartment of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, Sweden; Centre for Population Studies, Ageing and Living Conditions Programme, Umeå University, Umeå, Sweden.
Patrik WennbergDepartment of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden.
Bernt LindahlDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden.
Olov RolandssonDepartment of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Simon J GriffinMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Lars WeinehallDepartment of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, Sweden. Electronic address: lars.weinehall@epiph.umu.se.

Funding

Department of Health RP-PG-0606-1259Medical Research Council MC_U106179474Medical Research Council MC_UU_12015/4
6 · The paper itself

Abstract

backgroundComplementary strategies to shift risk factor population distributions and target high-risk individuals are required to reduce the burden of type 2 diabetes and cardiovascular disease (CVD). PURPOSE: To examine secular changes in glucose and CVD risk factors over 20 years during an individual and population-based CVD prevention program in Västerbotten County, Sweden.

methodsPopulation-based health promotion intervention was conducted and annual invitation for individuals turning 40, 50, and 60 years to attend a health assessment, including an oral glucose tolerance test, biochemical measures, and a questionnaire. Data were collected between 1991 and 2010, analyzed in 2012 and available for 120,929 individuals. Linear regression modeling examined age-adjusted differences in CVD risk factor means over time. Data were direct-age-standardized to compare disease prevalence.

resultsBetween 1991-1995 and 2006-2010, mean age-adjusted cholesterol (men=-0.53, 95% CI=-0.55, -0.50 mmol/L; women=-0.48, 95% CI=-0.50, -0.45 mmol/L) and systolic blood pressure declined (men=-3.06, 95% CI=-3.43, -2.70 mm Hg; women=-5.27, 95% CI=-5.64, -4.90 mm Hg), with corresponding decreases in the age-standardized prevalence of hypertension and hyperlipidemia. Mean age-adjusted 2-hour plasma glucose (men=0.19, 95% CI=0.15, 0.23 mmol/L; women=0.08, 95% CI=0.04, 0.11 mmol/L) and BMI increased (men=1.12, 95% CI=1.04, 1.21; women=0.65, 95% CI=0.55, 0.75), with increases in the age-standardized prevalence of diabetes and obesity.

conclusionsThese data demonstrate the potential of combined individual- and population-based approaches to CVD risk factor control and highlight the need for additional strategies addressing hyperglycemia and obesity.

Indexed as

Blood GlucoseBlood PressureBody Mass IndexHealth PromotionAdultCardiovascular DiseasesCholesterolFemaleHumansMaleMetabolic DiseasesMiddle AgedObesityPrevalenceRisk FactorsSwedenBlood GlucoseCholesterol

Identifiers

PMID24439344
PMCPMC3898870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.