ArticleBMC evolutionary biology2014
Evolutionary classification of ammonium, nitrate, and peptide transporters in land plants.
Article in BMC evolutionary biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 178 citations in OpenAlex.
- Plant ammonium sensitivity is associated with external pH adaptation, repertoire of nitrogen transporters, and nitrogen requirement.Journal of experimental botany · 2024Pooled it
- Genome-wide analyses of NPF and NRT2 reveal a potential role for a key gene, CqNRT2.2, in the quinoa response to nitrate.BMC plant biology · 2026Article
- Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack.The New phytologist · 2026Review
- Unraveling nitrogen uptake and metabolism: gene families, expression dynamics and functional insights in aspen (Populus tremula).Tree physiology · 2025Article
- Evolutionary trajectory of the NPF6.3(NRT1.1/CHL1)-centered nitrate signaling regulatory network in plant roots.BMC plant biology · 2025Article
- Nitrogen Use Efficiency in Agriculture: Integrating Biotechnology, Microbiology, and Novel Delivery Systems for Sustainable Agriculture.Plants (Basel, Switzerland) · 2025Review
- Genome-Wide Identification and Expression Analysis of PkNRT Gene Family in Korean Pine (Plants (Basel, Switzerland) · 2025Article
- Natural variation in the adjustment of primary metabolism determines ammonium tolerance in the model grass Brachypodium distachyon.Journal of experimental botany · 2024Article
- Genome-wide identification, evolution and expression analysis unveil the role ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Heat stress memory differentially regulates the expression of nitrogen transporter genes in the filamentous red alga 'Frontiers in plant science · 2024Article
- Transcription factor module NLP-NIGT1 fine-tunes NITRATE TRANSPORTER2.1 expression.Plant physiology · 2023Article
- Genome-wide identification and expression analysis of the NRT genes in Ginkgo biloba under nitrate treatment reveal the potential roles during calluses browning.BMC genomics · 2023Article
- Review
- Analysis of the AMT gene family in chili pepper and the effects of arbuscular mycorrhizal colonization on the expression patterns of CaAMT2 genes.BMC genomics · 2023Article
- Genome-Wide Identification and Expression Analysis ofPlants (Basel, Switzerland) · 2023Article
- Genome-Wide Identification and Characterization of Ammonium Transporter (AMT) Genes in Rapeseed (Genes · 2023Article
- Identification and functional characterization of the sugarcane (Frontiers in plant science · 2023Article
- Unlocking the potentials of nitrate transporters at improving plant nitrogen use efficiency.Frontiers in plant science · 2023Review
- Breeding for Higher Yields of Wheat and Rice through Modifying Nitrogen Metabolism.Plants (Basel, Switzerland) · 2022Review
- Nitrogen Acquisition and Transport in the Ectomycorrhizal Symbiosis-Insights from the Interaction between an Oak Tree andPlants (Basel, Switzerland) · 2022Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNitrogen uptake, reallocation within the plant, and between subcellular compartments involves ammonium, nitrate and peptide transporters. Ammonium transporters are separated into two distinct families (AMT1 and AMT2), each comprised of five members on average in angiosperms. Nitrate transporters also form two discrete families (NRT1 and NRT2), with angiosperms having four NRT2s, on average. NRT1s share an evolutionary history with peptide transporters (PTRs). The NRT1/PTR family in land plants usually has more than 50 members and contains also members with distinct activities, such as glucosinolate and abscisic acid transport.
resultsPhylogenetic reconstructions of each family across 20 land plant species with available genome sequences were supplemented with subcellular localization and transmembrane topology predictions. This revealed that both AMT families diverged prior to the separation of bryophytes and vascular plants forming two distinct clans, designated as supergroups, each. Ten supergroups were identified for the NRT1/PTR family. It is apparent that nitrate and peptide transport within the NRT1/PTR family is polyphyletic, that is, nitrate and/or peptide transport likely evolved multiple times within land plants. The NRT2 family separated into two distinct clans early in vascular plant evolution. Subsequent duplications occurring prior to the eudicot/monocot separation led to the existence of two AMT1, six AMT2, 31 NRT1/PTR, and two NRT2 clans, designated as groups.
conclusionPhylogenetic separation of groups suggests functional divergence within the angiosperms for each family. Distinct groups within the NRT1/PTR family appear to separate peptide and nitrate transport activities as well as other activities contained within the family, for example nitrite transport. Conversely, distinct activities, such as abscisic acid and glucosinolate transport, appear to have recently evolved from nitrate transporters.
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