Evidence map›Paper›PMID 24437603›Full record

ReviewConnective tissue research

The role of acidic phosphoproteins in biomineralization.

Keith Alvares

Open access · greenAbstract readReview
In one paragraph

Review in Connective tissue research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  10. [The latest study on biomimetic mineralized collagen-based bone materials for pediatric skull regeneration and repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Review
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  17. The secretory pathway kinases.Biochimica et biophysica acta · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Keith AlvaresDepartment of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University , Chicago, IL , USA.
Northwestern University · US

Funding

MATRIX COMPONENT INTERACTIONS IN BONE, DENTIN AND INVERTEBRATE MINERALR01DE001374 · NIDCR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ALVARES, KEITH, STOCK, STUART R · 1985 to 2013
$4.6M
MATRIX COMPONENT INTERACTIONS IN BONE AND DENTINR37DE001374 · NIDCR · NORTHWESTERN UNIVERSITY · PI VEIS, ARTHUR · 1988 to 1997
–
NIDCR NIH HHS DE001374NIDCR NIH HHS R01 DE001374
6 · The paper itself

Abstract

Biomineralization is the process by which living organisms deposit mineral in the extracellular matrix. In nature, almost 50% of biominerals are calcium-bearing minerals. In addition to calcium, we find biominerals formed from silica and magnetite. Calcium-containing biominerals could be either calcium phosphate as in apatite found in vertebrates or calcium carbonate as in calcite and aragonite found in many invertebrates. Since all biomineralization is matrix mediated, an understanding of the nature of the proteins involved is essential in elucidating its mechanism. This review will discuss some of the proteins involved in the process of biomineralization involving calcium. Two proteins, dentin matrix protein 1 and dentin phosphoprotein (Phosphophoryn) will serve as models for the vertebrate system, and two others - P16 and phosphodontin will serve as models for the invertebrate system.

Indexed as

Calcification, PhysiologicAcidsAmino Acid SequenceAnimalsHumansInvertebratesMolecular Sequence DataPhosphoproteinsVertebratesAcidsPhosphoproteins

Identifiers

PMID24437603
PMCPMC4005356
OpenAlexW2042815255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.