ArticleEvidence-based spine-care journal2013
Thoracic spinal metastasis of merkel cell carcinoma in an immunocompromised patient: case report.
Article in Evidence-based spine-care journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Review
- Treatment of Merkel cell carcinoma in organ transplant recipients-A systematic review.JAAD international · 2025Review
- Intradural extramedullary cervical metastasis from Merkel cell carcinoma: a case report and literature review.Chinese neurosurgical journal · 2022Article
- A thoracic vertebral localization of a metastasized cutaneous Merkel cell carcinoma: Case report and review of literature.Surgical neurology international · 2017Article
- Solitary Spinal Epidural Metastasis from Prostatic Small Cell Carcinoma.Case reports in radiology · 2016Article
- Merkel Cell Spinal Metastasis: Management in the Setting of a Poor Prognosis.Global spine journal · 2015Article
- Merkel cell carcinoma presenting as malignant ascites: A case report and review of literature.CytoJournal · 2015Article
- A unique case of merkel cell carcinoma with ovarian metastasis.Balkan medical journal · 2014Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study Design Case report. Objective Merkel cell carcinoma (MCC), an uncommon cutaneous neuroendocrine malignancy, is a rare cause of spinal metastasis, with only five cases previously reported. We report a rare case of MCC metastatic to the spine in an immunocompromised patient. Methods A 55-year-old male with previously resected MCC, immunocompromised due to cardiac transplant, presented with sharp mid-thoracic back pain radiating around the trunk to the midline. Computed tomography of the thoracic spine showed a dorsal epidural mass from T6 to T8 with compression of the spinal cord. Laminectomy and subtotal tumor resection were performed, and pathology confirmed Merkel cell tumor through immunohistochemistry staining positive for cytokeratin 20 and negative for thyroid transcription factor-1. Results Further treatment with radiation therapy was initiated, and the patient did well for 4 months after surgery, but returned with a lesion in the cervical spine. He then opted for hospice care. Conclusions With an increasing number of immunocompromised patients presenting with back pain, MCC should be considered in the differential diagnosis of spinal metastatic disease.
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