ReviewEvidence-based spine-care journal2013
The outcomes of manipulation or mobilization therapy compared with physical therapy or exercise for neck pain: a systematic review.
Review in Evidence-based spine-care journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Manual therapy for non-radicular cervical spine related impairments: establishing a 'Trustworthy' living systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2023Pooled it
- Manipulation and Mobilization for Treating Chronic Nonspecific Neck Pain: A Systematic Review and Meta-Analysis for an Appropriateness Panel.Pain physician · 2019Pooled it
- Manipulation and mobilization for treating chronic low back pain: a systematic review and meta-analysis.The spine journal : official journal of the North American Spine Society · 2018Pooled it
- The risk associated with spinal manipulation: an overview of reviews.Systematic reviews · 2017Pooled it
- Exercises for mechanical neck disorders.The Cochrane database of systematic reviews · 2015Pooled it
- Integrating Chiropractic Care and Tai Chi Training for the Treatment of Chronic Nonspecific Neck Pain in Nurses: A Single-Arm Mixed-Methods Pilot Trial.Journal of integrative and complementary medicine · 2024Trial
- Effects of local treatment with and without sensorimotor and balance exercise in individuals with neck pain: protocol for a randomized controlled trial.BMC musculoskeletal disorders · 2018Trial
- Efficacy of a modern neuroscience approach versus usual care evidence-based physiotherapy on pain, disability and brain characteristics in chronic spinal pain patients: protocol of a randomized clinical trial.BMC musculoskeletal disorders · 2014Trial
- The Effect of Joint Mobilization and Manipulation on Proprioception: Systematic Review with Limited Meta-Analysis.Journal of functional morphology and kinesiology · 2026Review
- Combined chiropractic care and Tai Chi for chronic neck pain: A protocol for a pilot randomized trial.Contemporary clinical trials communications · 2025Article
- Effects of Global Postural Re-Education Versus Specific Therapeutic Exercises on Pain, Head Posture, and Pain-Related Psychosocial Factors in Women with Chronic Nonspecific Neck Pain: A Randomized Clinical Trial.Journal of clinical medicine · 2025Article
- Protocol for the development of a 'trustworthy' living systematic review and meta analyses of manual therapy interventions to treat neuromusculoskeletal impairments.The Journal of manual & manipulative therapy · 2023Article
- Effectiveness of manual therapy, computerised mobilisation plus home exercise, and home exercise only in treating work-related neck pain: study protocol for a randomised controlled trial.BMC musculoskeletal disorders · 2022Article
- Health Care Resource Utilization in Management of Opioid-Naive Patients With Newly Diagnosed Neck Pain.JAMA network open · 2022Article
- Effects of Global Postural Reeducation versus Specific Therapeutic Neck Exercises on Pain, Disability, Postural Control, and Neuromuscular Efficiency in Women with Chronic Nonspecific Neck Pain: Study Protocol for a Randomized, Parallel, Clinical Trial.International journal of environmental research and public health · 2021Article
- The effect of osteopathic medicine on pain in musicians with nonspecific chronic neck pain: a randomized controlled trial.Therapeutic advances in musculoskeletal disease · 2020Article
- Health care contact following a new incident neck or low back pain episode in the general population; the HUNT study.BMC health services research · 2016Article
- The Effect of Physical Therapy Treatment in Patients with Subjective Tinnitus: A Systematic Review.Frontiers in neuroscience · 2016Review
- Applying contemporary neuroscience in exercise interventions for chronic spinal pain: treatment protocol.Brazilian journal of physical therapyArticle
- Trends in management of myofacial pain.National journal of maxillofacial surgeryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study Design Systematic review. Study Rationale Neck pain is a prevalent condition. Spinal manipulation and mobilization procedures are becoming an accepted treatment for neck pain. However, data on the effectiveness of these treatments have not been summarized. Objective To compare manipulation or mobilization of the cervical spine to physical therapy or exercise for symptom improvement in patients with neck pain. Methods A systematic review of the literature was performed using PubMed, the National Guideline Clearinghouse Database, and bibliographies of key articles, which compared spinal manipulation or mobilization therapy with physical therapy or exercise in patients with neck pain. Articles were included based on predetermined criteria and were appraised using a predefined quality rating scheme. Results From 197 citations, 7 articles met all inclusion and exclusion criteria. There were no differences in pain improvement when comparing spinal manipulation to exercise, and there were inconsistent reports of pain improvement in subjects who underwent mobilization therapy versus physical therapy. No disability improvement was reported between treatment groups in studies of acute or chronic neck pain patients. No functional improvement was found with manipulation therapy compared with exercise treatment or mobilization therapy compared with physical therapy groups in patients with acute pain. In chronic neck pain subjects who underwent spinal manipulation therapy compared to exercise treatment, results for short-term functional improvement were inconsistent. Conclusion The data available suggest that there are minimal short- and long-term treatment differences in pain, disability, patient-rated treatment improvement, treatment satisfaction, health status, or functional improvement when comparing manipulation or mobilization therapy to physical therapy or exercise in patients with neck pain. This systematic review is limited by the variability of treatment interventions and lack of standardized outcomes to assess treatment benefit.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.