Evidence map›Paper›PMID 24436470›Full record

ArticleJournal of the American Society of Nephrology : JASN2014

Geographic determinants of access to pediatric deceased donor kidney transplantation.

Peter P Reese, Hojun Hwang, Vishnu Potluri, Peter L Abt, Justine Shults, Sandra Amaral

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Predicting wait time for pediatric kidney transplant: a novel index.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  4. Article
  5. Transplant access for children: there is more to be done.Pediatric nephrology (Berlin, Germany) · 2023
    Article
  6. Effect of Policy on Geographic Inequities in Kidney Transplantation.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Article
  7. Allocating kidneys in optimized heterogeneous circles.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Inequality in pediatric kidney transplantation in Brazil.Pediatric nephrology (Berlin, Germany) · 2016
    Article
  13. Association of Body Mass Index with Patient-Centered Outcomes in Children with ESRD.Journal of the American Society of Nephrology : JASN · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peter P ReeseRenal-Electrolyte and Hypertension Division, Perelman School of Medicine.
Hojun Hwang
Vishnu Potluri
Peter L Abt
Justine Shults
Sandra Amaral

Funding

Assessing an adherence intervention for adolescents with kidney transplantsK23DK083529 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI AMARAL, SANDRA · 2011 to 2015
$861k
Measuring Living Kidney Transplantation at Renal Transplant CentersK23DK078688 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI REESE, PETER PHILIP · 2007 to 2011
$658k
NIDDK NIH HHS K23 DK078688NIDDK NIH HHS K23-DK078688NIDDK NIH HHS K23 DK083529NIDDK NIH HHS K23-DK083529
6 · The paper itself

Abstract

Children receive priority in the allocation of deceased donor kidneys for transplantation in the United States, but because allocation begins locally, geographic differences in population and organ supply may enable variation in pediatric access to transplantation. We assembled a cohort of 3764 individual listings for pediatric kidney transplantation in 2005-2010. For each donor service area, we assigned a category of short (<180 days), medium (181-270 days), or long (>270 days) median waiting time and calculated the ratio of pediatric-quality kidneys to pediatric candidates and the percentage of these kidneys locally diverted to adults. We used multivariable Cox regression analyses to examine the association between donor service area characteristics and time to deceased donor kidney transplantation. The Kaplan-Meier estimate of median waiting time to transplantation was 284 days (95% confidence interval, 263 to 300 days) and varied from 14 to 1313 days across donor service areas. Overall, 29% of pediatric-quality kidneys were locally diverted to adults. Compared with areas with short waiting times, areas with long waiting times had a lower ratio of pediatric-quality kidneys to candidates (3.1 versus 5.9; P<0.001) and more diversions to adults (31% versus 27%; P<0.001). In multivariable regression, a lower kidney to candidate ratio remained associated with longer waiting time (hazard ratio, 0.56 for areas with <2:1 versus reference areas with ≥5:1 kidneys/candidates; P<0.01). Large geographic variation in waiting time for pediatric deceased donor kidney transplantation exists and is highly associated with local supply and demand factors. Future organ allocation policy should address this geographic inequity.

Indexed as

Health Services AccessibilityKidney TransplantationAdolescentChildChild, PreschoolFemaleHumansInfantMaleProportional Hazards ModelsTissue DonorsWaiting Lists

Identifiers

PMID24436470
PMCPMC3968505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.