Evidence map›Paper›PMID 24436366›Full record

ArticleArchives of disease in childhood2014

Guidelines to identify abnormalities after childhood urinary tract infections: a prospective audit.

Malcolm G Coulthard, Heather J Lambert, Susan J Vernon, Elizabeth W Hunter, Michael J Keir

Abstract readComparative Study
In one paragraph

Article in Archives of disease in childhood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Malcolm G CoulthardPaediatric Nephrology Unit, Great North Children's Hospital, , Newcastle, UK.
Heather J Lambert
Susan J Vernon
Elizabeth W Hunter
Michael J Keir

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the childhood urinary tract infection (UTI) guidelines from the Royal College of Physicians (RCP) in 1991 and from National Institute of Health and Care Excellence (NICE) (CG54) in 2007 by measuring their efficiency at detecting urinary tract abnormalities.

designChildren with UTIs within the Newcastle Primary Care Trust (population 70,800 children) were referred and imaged according to the RCP guidelines during 2008, and these were compared to the activity that would have been undertaken if we had implemented the CG54 guidelines, including following them through 2011 to identify those with recurrent UTIs.

main outcome measuresThe numbers of children imaged, the imaging burden and efficiency, and urinary tract abnormalities detected by each guideline.

resultsFewer children would have been imaged by CG54 than RCP (150 vs 427), but its sensitivity was lower, at 44% for detecting scarring, 10% for identifying vesicoureteric reflux and 40% for other abnormalities. Overall, it would have only detected one-quarter of the abnormal cases (8 vs 32) and would have missed five of nine children with scarring, including three with multiple lesions and one with renal impairment. Imposing an age restriction of <8 years to the RCP guidelines would reduce its screening rate by 20% and still detect 90% of the abnormalities.

interpretationThe CG54 guidelines do not alter the imaging efficiency compared to the RCP guidelines, but they are considerably less sensitive.

Indexed as

Medical AuditPractice Guidelines as TopicRadiopharmaceuticalsTechnetium Tc 99m Dimercaptosuccinic AcidAdolescentChildChild, PreschoolFemaleGuideline AdherenceHumansInfantKidney DiseasesMaleOutcome Assessment, Health CareProspective StudiesRadionuclide ImagingRadiopharmaceuticalsTechnetium Tc 99m Dimercaptosuccinic Acidrenal scarringurinary tract imagingurinary tract infectionvesicoureteric reflux

Identifiers

PMID24436366
PMCPMC3995217

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.