Evidence map›Paper›PMID 24436130›Full record

ArticleProteomics2014

The Equine PeptideAtlas: a resource for developing proteomics-based veterinary research.

Louise Bundgaard, Stine Jacobsen, Mette A Sørensen, Zhi Sun, Eric W Deutsch, Robert L Moritz, Emøke Bendixen

Open access · greenAbstract read
In one paragraph

Article in Proteomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  8. Review
  9. Article
  10. Animal board invited review: advances in proteomics for animal and food sciences.Animal : an international journal of animal bioscience · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Louise BundgaardDepartment of Large Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Molecular Biology and Genetics, Faculty of Science and Technology, Aarhus University, Aarhus, Denmark.
Stine Jacobsen
Mette A Sørensen
Zhi Sun
Eric W Deutsch
Robert L Moritz
Emøke Bendixen
Institute for Systems Biology · USAarhus University · DKUniversity of Copenhagen · DK

Funding

Quantitative Systems BiologyP50GM076547 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI BALIGA, NITIN S · 2006 to 2016
$30.6M
Shortening the development cycle time of Trans Proteomic Pipeline tools with high performance computingR01GM087221 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI DEUTSCH, ERIC, MORITZ, ROBERT L · 2010 to 2021
$6.0M
Complete Human Peptide- and MRM-AtlasRC2HG005805 · NHGRI · INSTITUTE FOR SYSTEMS BIOLOGY · PI HOOD, LEROY E, MORITZ, ROBERT L · 2009 to 2010
$4.6M
NHGRI NIH HHS RC2 HG005805NIGMS NIH HHS 2P50 GM076547NIGMS NIH HHS P50 GM076547NIGMS NIH HHS R01 GM087221
6 · The paper itself

Abstract

Progress in MS-based methods for veterinary research and diagnostics is lagging behind compared to the human research, and proteome data of domestic animals is still not well represented in open source data repositories. This is particularly true for the equine species. Here we present a first Equine PeptideAtlas encompassing high-resolution tandem MS analyses of 51 samples representing a selection of equine tissues and body fluids from healthy and diseased animals. The raw data were processed through the Trans-Proteomic Pipeline to yield high quality identification of proteins and peptides. The current release comprises 24 131 distinct peptides representing 2636 canonical proteins observed at false discovery rates of 0.2% at the peptide level and 1.4% at the protein level. Data from the Equine PeptideAtlas are available for experimental planning, validation of new datasets, and as a proteomic data mining resource. The advantages of the Equine PeptideAtlas are demonstrated by examples of mining the contents for information on potential and well-known equine acute phase proteins, which have extensive general interest in the veterinary clinic. The extracted information will support further analyses, and emphasizes the value of the Equine PeptideAtlas as a resource for the design of targeted quantitative proteomic studies.

Indexed as

Amino Acid SequenceAnimalsDatabases, ProteinData MiningHorse DiseasesHorsesHumansMolecular Sequence DataPeptidesProteomeProteomicsTandem Mass SpectrometryPeptidesProteomeAcute phase proteinsAnimal proteomicsEquinePeptideAtlasProteotypic peptides

Identifiers

PMID24436130
PMCPMC4340707
OpenAlexW2022641364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.