Evidence map›Paper›PMID 24435888›Full record

ArticleBMJ open2014

Analysis of the bereavement effect after the death of a spouse in the Amish: a population-based retrospective cohort study.

Ari Seifter, Sarabdeep Singh, Patrick F McArdle, Kathleen A Ryan, Alan R Shuldiner, Braxton D Mitchell, Alejandro A Schäffer

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ari SeifterDepartment of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Sarabdeep Singh
Patrick F McArdle
Kathleen A Ryan
Alan R Shuldiner
Braxton D Mitchell
Alejandro A Schäffer
University of Maryland, Baltimore · USUnited States Department of Veterans Affairs · USNational Center for Biotechnology Information · USNational Institutes of Health · US

Funding

Genome-wide Search for CVD Gene-Environment InteractionsU01HL072515 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2002 to 2008
$11.2M
GENETICS OF DIABETES IN THE AMISHR01DK054261 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2000 to 2009
$5.1M
Case Studies In GeneticsZIALM000097 · NLM · NATIONAL LIBRARY OF MEDICINE · PI SCHAFFER, ALEJANDRO A · 2009 to 2019
$4.6M
Longevity Genes in Founder PopulationsR01AG018728 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2001 to 2005
$3.8M
Genetic Influences on Coronary Artery CalcificationR01HL088119 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2007 to 2010
$2.8M
GENETICS OF OSTEOPOROSIS IN THE AMISHR01AR046838 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2000 to 2004
$2.7M
Joint Determinants of Bone Density and CVD CalcificationR01HL069313 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2001 to 2004
$1.4M
Short-term Training Program on AgingT35AG036679 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI CAREY, GREGORY B · 2010 to 2014
$704k
NHLBI NIH HHS R01 HL069313NHLBI NIH HHS R01 HL088119NHLBI NIH HHS R01 HL69313NHLBI NIH HHS U01 HL072515NHLBI NIH HHS U01 HL72515NIAMS NIH HHS R01 AR046838NIA NIH HHS R01 AG1872801NIA NIH HHS T35 AG036679NIDDK NIH HHS R01 DK054261NIDDK NIH HHS R01 DK54261
6 · The paper itself

Abstract

objectiveThis study investigates the association between bereavement and the mortality of a surviving spouse among Amish couples. We hypothesised that the bereavement effect would be relatively small in the Amish due to the unusually cohesive social structure of the Amish that might attenuate the loss of spousal support.

designPopulation-based cohort study.

settingThe USA.

participants10,892 Amish couples born during 1725-1900 located in Pennsylvania, Ohio and Indiana. All the participants are deceased. OUTCOME MEASURES: The survival time is 'age'; event is 'death'. Hazard ratios (HRs) of widowed individuals with respect to gender, age at widowhood, remarriage, the number of surviving children and time since bereavement.

resultsWe observed HRs for widowhood ranging from 1.06 to 1.26 over the study period (nearly all differences significant at p<0.05). Mortality risks tended to be higher in men than in women and in younger compared with older bereaved spouses. There were significantly increased mortality risks in widows and widowers who did not remarry. We observed a higher number of surviving children to be associated with increased mortality in men and women. Mortality risk following bereavement was higher in the first 6 months among men and women.

conclusionsWe conclude that bereavement effects remain apparent even in this socially cohesive Amish community. Remarriage is associated with a significant decrease in the mortality risk among Amish individuals. Contrary to results from previous studies, an increase in the number of surviving children was associated with decreased survival rate.

Indexed as

BereavementAmishCohort StudiesFemaleHumansMaleMarriageMiddle AgedMortalityRetrospective StudiesWidowhoodEpidemiologyGeriatric MedicineMental HealthPublic Health

Identifiers

PMID24435888
PMCPMC3902313
OpenAlexW2058346748

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.