ArticleClinical research in cardiology : official journal of the German Cardiac Society2014
Use of drug-eluting stents in acute myocardial infarction with persistent ST-segment elevation: results of the ALKK PCI-registry.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- External validity of the "all-comers" design: insights from the BIOSCIENCE trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Trial
- Efficacy of Drug-Eluting Stents in Diabetic Patients Admitted with ST-Elevation Myocardial Infarctions Treated with Primary Percutaneous Coronary Intervention.Journal of cardiovascular development and disease · 2021Article
- Quantitative myocardial blush score (QuBE) allows the prediction of heart failure development in long-term follow-up in patients with ST-segment elevation myocardial infarction: Proof of concept study.Cardiology journal · 2019Article
- Early diagnosis of acute myocardial infarction in patients with mild elevations of cardiac troponin.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Real-world use of fractional flow reserve in Germany: results of the prospective ALKK coronary angiography and PCI registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Safety of percutaneous coronary intervention in patients with acute ischemic stroke/transient ischemic attack and acute coronary syndrome.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
- Use and impact of thrombectomy in primary percutaneous coronary intervention for acute myocardial infarction with persistent ST-segment elevation: results of the prospective ALKK PCI-registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Coronary procedures in German hospitals: a detailed analysis for specific patient clusters.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Uncommon cause of ST-segment elevation in V1-V3: incremental value of cardiac magnetic resonance imaging.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Article
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Authors and funding
10 authors at 7 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDrug-eluting stents (DES) reduce the rate of in-stent restenosis (ISR) and target vessel revascularization significantly when compared with bare metal stents (BMS). Their beneficial effects have been demonstrated in patients with acute myocardial infarction also, but the use of DES in the latter population seems to be still limited in clinical practice. METHODS AND
resultsFrom January 2006 to December 2011, 25,424 patients with ST-elevation myocardial infarction were enrolled in the German ALKK PCI-registry. In 5,467 patients (21.5 %), a DES was implanted in the culprit segment, in 16,911 patients (66.5 %) a BMS, and 2,959 patients (11.6 %) received neither DES nor BMS. The rates of DES for typical subgroups were 31.7 % in patients with diabetes, 36.6 % in unprotected left main stenosis, 32.4 % in ostial lesions, 32.0 % for a stent length >15 mm, 26.2 % for a stent diameter ≤3 mm, and 58.5 % for ISR. There was a wide range in the use of DES between the different ALKK hospitals with a minimum of 2.3 % and a maximum of 58.3 % for the total study period (median 22.0 %, quartiles 14.6 and 37.5 %).
conclusionsDespite convincing data for the use of DES in patients with STEMI, there is still an underuse of DES in this clinical setting in Germany. This is particularly worrying for the subgroups of patients and lesions with a high risk of restenosis. Further efforts are needed to reduce the skepticism about DES and to improve guideline adherent treatment.
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