ArticleScientific reports2014
Molecular detection of Lactobacillus species in the neovagina of male-to-female transsexual women.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Microbial community structure and source contribution to the early neovaginal microbiota following penile inversion vaginoplasty.Frontiers in cellular and infection microbiology · 2026Article
- The neovaginal microbiota, symptoms, and local immune correlates in transfeminine individuals with penile inversion vaginoplasty.Cell reports · 2025Article
- The Vaginal Microbiome of Transgender and Gender Nonbinary Individuals.Transgender health · 2024Article
- Harnessing the power within: engineering the microbiome for enhanced gynecologic health.Reproduction & fertility · 2024Review
- The microbiome of the neovagina: a systematic review and comparison of surgical techniques.International journal of transgender health · 2024Review
- Neovaginal discharge in transgender women after vaginoplasty: A diagnostic and treatment algorithm.International journal of transgender health · 2020Article
- Specific vaginal lactobacilli suppress the inflammation induced by lipopolysaccharide stimulation through downregulation of toll-like receptor 4 expression in human embryonic intestinal epithelial cells.Bioscience of microbiota, food and health · 2017Article
- Using an in-vitro biofilm model to assess the virulence potential of bacterial vaginosis or non-bacterial vaginosis Gardnerella vaginalis isolates.Scientific reports · 2015Article
- [Researcher of the month].Wiener klinische Wochenschrift · 2015Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a general opinion that penile skin lined neovagina of transsexual women is not able to support the growth of lactobacilli. This study was undertaken to prove if lactobacilli strains could survive in neovagina and to characterise the most dominant Lactobacillus species. Sixty three male-to-female transsexual women without abnormal vaginal discharge, clinical signs of infection were recruited on an ongoing basis from among transsexual outpatients in an academic research institution and tertiary care centre. Neovaginal smears were taken for molecular Lactobacillus spp. profiling by denaturing gradient gel electrophoresis (PCR-DGGE). Lactobacillus species were detected from 47/63 transsexual women (75%). The 279 Lactobacillus signals detected by PCR-DGGE technique belonged to 13 different species. Lactobacilli of the L. delbrueckii group (L. gasseri, L. crispatus, L. johnsonii, L. iners, L. jensenii) were predominant. More than 90% of women harboured a combination of two or more neovaginal Lactobacillus species. In this study we report the frequent occurrence of lactobacilli from neovagina of transsexual women. Both, frequency and composition were similar to the normal lactic acid bacterial microflora in both women of reproductive age and postmenopausal women.
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