Evidence map›Paper›PMID 24434783›Full record

Trial reportBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2014

Adjustment in parents of children undergoing stem cell transplantation.

Jennifer J Lindwall, Kathy Russell, Qinlei Huang, Hui Zhang, Kathryn Vannatta, Maru Barrera, Melissa Alderfer, Sean Phipps

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Meditation for adults with haematological malignancies.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2023
    Article
  8. Trajectories of resilience and posttraumatic stress in childhood cancer: Consistency of child and parent outcomes.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Parents of Children With Cancer: At-Risk or Resilient?Journal of pediatric psychology · 2015
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer J LindwallDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee; Department of Psychiatry and Behavioral Sciences, Children's Hospital of Colorado, Aurora, Colorado.
Kathy RussellDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Qinlei HuangDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Hui ZhangDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Kathryn VannattaCenter for Biobehavioral Heatlh, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Maru BarreraDepartment of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Melissa AlderferDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Sean PhippsDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address: sean.phipps@stjude.org.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Psychosocial Impact of Pediatric Bone Marrow TransplantR01CA060616 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI PHIPPS, SEAN · 2002 to 2006
$1.8M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA060616NCI NIH HHS R01 CA60616
6 · The paper itself

Abstract

Pediatric stem cell transplantation (SCT) is a demanding procedure for children and parents. Interventions to promote positive adjustment of parents in this setting are needed. A total of 171 patient-parent dyads from 4 sites received 1 of 3 interventions to reduce SCT-related distress: a child intervention with massage and humor therapy, an identical child intervention plus a parent intervention with massage and relaxation/imagery, or standard care. Parents completed weekly self-report measures of distress and positive affect during the acute phase of treatment (weeks -1 through +6); and measures of depression, posttraumatic stress (PTSD), and benefit finding at baseline and week +24. No significant differences across treatment arms were observed on repeated measures of parental distress. There was a marginally significant effect of the child intervention on parental positive affect. Over time, parental distress decreased significantly and positive affect increased significantly in all groups. Similarly, there were no significant intervention effects on the global adjustment outcomes of depression, PTSD, and benefit finding. However, reports of depression and PTSD decreased significantly and reports of benefit finding increased significantly from baseline to week +24 for all groups. Across all study arms, parent adjustment improved over time, suggesting that parents demonstrate a transient period of moderately elevated distress at the time of their child's admission for transplantation, followed by rapid improved to normative levels of adjustment. Similar to results previously reported for their children, these parents appear resilient to the challenges of transplantation.

Indexed as

Adaptation, PsychologicalAdolescentAdultChildDepressionFemaleHematologic NeoplasmsHumansMaleParentsRelaxation TherapyStem Cell TransplantationStress, PsychologicalSurvival AnalysisTransplantation, AutologousTransplantation, HomologousParent adjustmentPediatric cancerStem cell transplantation

Identifiers

PMID24434783
PMCPMC3963285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.