ReviewGeneral and comparative endocrinology2014
Prolactin and teleost ionocytes: new insights into cellular and molecular targets of prolactin in vertebrate epithelia.
Review in General and comparative endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 85 citations in OpenAlex.
- Serotonin stimulates proliferation of ionocytes via the 5-HT2A receptor in zebrafish larvae.The Journal of experimental biology · 2026Article
- Endocrine control of gill ionocyte function in euryhaline fishes.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Review
- Triphenyl phosphate-induced pericardial edema in zebrafish embryos is reversible following depuration in clean water.Aquatic toxicology (Amsterdam, Netherlands) · 2023Article
- Osmosensitive transcription factors in the prolactin cell of a euryhaline teleost.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023Article
- Effects of Osmotic Stress on the mRNA Expression ofInternational journal of molecular sciences · 2023Article
- Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media.Environment international · 2023Article
- NaJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Article
- Tilapia prolactin cells are thermosensitive osmoreceptors.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands.Cell reports · 2022Article
- Differential Branchial Response of Low Salinity Challenge Induced Prolactin in Active and Passive Coping Style Olive Flounder.Frontiers in physiology · 2022Article
- The Origination of Growth Hormone/Insulin-Like Growth Factor System: A Story From Ancient Basal Chordate Amphioxus.Frontiers in endocrinology · 2022Review
- Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka.Communications biology · 2021Article
- Article
- Larval Zebrafish Use Olfactory Detection of Sodium and Chloride to Avoid Salt Water.Current biology : CB · 2021Article
- Characterization of a member of the CEACAM protein family as a novel marker of proton pump-rich ionocytes on the zebrafish epidermis.PloS one · 2021Article
- Transcriptional regulation of prolactin in a euryhaline teleost: Characterisation of gene promoters through in silico and transcriptome analyses.Journal of neuroendocrinology · 2020Review
- Divergent genes encoding the putative receptors for growth hormone and prolactin in sea lamprey display distinct patterns of expression.Scientific reports · 2020Article
- Secretion and Function of Pituitary Prolactin in Evolutionary Perspective.Frontiers in neuroscience · 2020Review
- Differential Expression and Localization of Branchial AQP1 and AQP3 in Japanese Medaka (Cells · 2019Article
- The effects of transfer from steady-state to tidally-changing salinities on plasma and branchial osmoregulatory variables in adult Mozambique tilapia.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The peptide hormone prolactin is a functionally versatile hormone produced by the vertebrate pituitary. Comparative studies over the last six decades have revealed that a conserved function for prolactin across vertebrates is the regulation of ion and water transport in a variety of tissues including those responsible for whole-organism ion homeostasis. In teleost fishes, prolactin was identified as the "freshwater-adapting hormone", promoting ion-conserving and water-secreting processes by acting on the gill, kidney, gut and urinary bladder. In mammals, prolactin is known to regulate renal, intestinal, mammary and amniotic epithelia, with dysfunction linked to hypogonadism, infertility, and metabolic disorders. Until recently, our understanding of the cellular mechanisms of prolactin action in fishes has been hampered by a paucity of molecular tools to define and study ionocytes, specialized cells that control active ion transport across branchial and epidermal epithelia. Here we review work in teleost models indicating that prolactin regulates ion balance through action on ion transporters, tight-junction proteins, and water channels in ionocytes, and discuss recent advances in our understanding of ionocyte function in the genetically and embryonically accessible zebrafish (Danio rerio). Given the high degree of evolutionary conservation in endocrine and osmoregulatory systems, these studies in teleost models are contributing novel mechanistic insight into how prolactin participates in the development, function, and dysfunction of osmoregulatory systems across the vertebrate lineage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.