ArticleAnnals of translational medicine2013
Functional role of microvesicles in gastrointestinal malignancies.
Article in Annals of translational medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Choosing the Right Extracellular Vesicle: Cross-Kingdom Immunological Functions Linking Molecular Mechanisms to Therapeutic Applications.Biomolecules · 2026Review
- Extracellular microvesicles: biologic properties, biogenesis, and applications in leukemia.Molecular and cellular biochemistry · 2024Review
- Tracking tools of extracellular vesicles for biomedical research.Frontiers in bioengineering and biotechnology · 2022Review
- Extracellular vesicles: General features and usefulness in diagnosis and therapeutic management of colorectal cancer.World journal of gastrointestinal oncology · 2021Review
- Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles.Science (New York, N.Y.) · 2018Article
- Interactions of tumour-derived micro(nano)vesicles with human gastric cancer cells.Journal of translational medicine · 2015Article
- Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology.World journal of gastroenterology · 2015Article
- microRNA-218 increase the sensitivity of gastrointestinal stromal tumor to imatinib through PI3K/AKT pathway.Clinical and experimental medicine · 2015Article
- RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OPN.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- miR-34a regulates cisplatin-induce gastric cancer cell death by modulating PI3K/AKT/survivin pathway.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Microvesicles (MVs) are derived from the plasma membrane and are released into the intracellular space by outward budding and fission of the plasma membrane of cells. Various studies have shown high regulation of microvesicles shedding from cells widespread throughout the body, often involving cancerous cells. MVs are originated from the endosomal membrane compartment, and after fusion with the plasma membrane, they are shed from the cell surface of activated cells. Therefore, microvesicles may be secreted by activated malignant and normal cells and play a role in cellular communication during cancer development. Microvesicles are found in many biological fluids in the body and have been demonstrated to receive their functionality from the parent cell from which they are derived. MVs facilitate the transfer of proteins and other molecules, thereby allowing for interaction with cells and tissues far away from the originating cell. This functionality has caused researchers to view microvesicles as a primary component of tumor progression and development. This commentary summarizes recent literature on the properties and biogenesis of microvesicles, and their influence on gastrointestinal tumor progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.