Evidence map›Paper›PMID 24431533›Full record

ReviewJournal of parasitic diseases : official organ of the Indian Society for Parasitology2013

Immunological disturbances associated with malarial infection.

Vandana Pradhan, Kanjaksha Ghosh

Abstract readReview
In one paragraph

Review in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vandana PradhanDepartment of Clinical and Experimental Immunology, National Institute of Immunohaematology, Indian Council of Medical Research, New Multistoryed Building, 13th Floor, King Edward Memorial Hospital Campus, Parel, Mumbai, 400012 India.
Kanjaksha GhoshDepartment of Clinical and Experimental Immunology, National Institute of Immunohaematology, Indian Council of Medical Research, New Multistoryed Building, 13th Floor, King Edward Memorial Hospital Campus, Parel, Mumbai, 400012 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is a reemerging disease in the countries where it was eradicated previously, whereas it is endemic in many countries including tropical countries. In India, malarial infection is on rise due to rapid urbanization and overcrowding in all major metropolitan cities. The incidence of morbidity and mortality due to malaria infection is increasing and could be attributed to drug resistance in strains of malarial parasite. Combining immune modulation strategies with anti-malarial drugs has a beneficial effect in an attempt to improve treatment for malaria. Along with clinical presentation and outcome of this parasitic infection, it is important to understand immunological disturbances associated with biological mechanisms underlying these actions in better understanding of pathogenesis of malarial infection. Immune and inflammatory responses in malarial infection are controlled and co-ordinated by various cytokines and chemokines. This review focuses on commonly seen immunological disturbances associated with malarial infection resulting in related humoral and cell mediated immune functions primarily with innate to subsequent adaptive immunity in tackling this parasitic infection.

Indexed as

Clinical complicationsImmune disturbancesMalariaP. falciparum

Identifiers

PMID24431533
PMCPMC3590368

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.