Evidence map›Paper›PMID 24430434›Full record

ArticlePituitary2015

Pituitary adenoma with gangliocytic component: report of 5 cases with focus on immunoprofile of gangliocytic component.

Serdar Balci, Arzu Saglam, Hakan Oruckaptan, Tomris Erbas, Figen Soylemezoglu

Abstract read
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In one paragraph

Article in Pituitary, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Serdar BalciPatoloji Anabilim Dalı, Hacettepe Üniversitesi Tıp Fakültesi, Morfoloji Binası 5.Kat. Sıhhiye, 06100, Ankara, Turkey.
Arzu Saglam
Hakan Oruckaptan
Tomris Erbas
Figen Soylemezoglu
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPituitary adenomas with gangliocytic component are rare tumors of the sellar region that are composed of pituitary adenoma cells and a ganglion cell component. Their histogenesis and hence nosology is not yet resolved because of the small number of cases reported and lack of large series in the literature.

methodsHerein we report five cases of pituitary adenoma with gangliocytic component to add knowledge to this rare neoplasm.

resultsThree cases are functional mammosomatotroph adenomas, one case is functional sparsely granulated somatotroph adenoma and the other is functional corticotroph adenoma. Gangliocytic component showed immunohistochemical expression of hormones in three cases. The ganglion cells were prolactin immunoreactive in case 1, GH and TSH immunoreactive in case 5 and showed expression of prolactin, TSH, ACTH and FSH in case 4. Three cases had undergone more than one surgery of which two had gangliocytic cells only in the recurrent tumors whereas the third case showed gangliocytic cells only in the initial tumor. DISCUSSION: The cases are discussed with clinical and histological features and a brief review of the literature considering the histogenesis is included.

Indexed as

AdenomaAdultFemaleGanglioneuromaHumansMiddle AgedPituitary Neoplasms

Identifiers

PMID24430434
OpenAlexW2062499263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.