ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2014
Plasma interleukin 33 level in patients with osteonecrosis of femoral head: an alarmin for osteonecrosis of the femoral head?
Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Osteonecrosis of the femoral head: genetic basis.International orthopaedics · 2019Pooled it
- Clinical Characteristics, Current Treatment Options, Potential Mechanisms, Biomarkers, and Therapeutic Targets in Avascular Necrosis of Femoral Head.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024Review
- Plasma Interleukin-33 Cannot Predict Hip Osteonecrosis in Patients With Sickle Cell Disease: A Case-Control Study.Cureus · 2022Article
- Plasma lipidomics analysis reveals altered lipids signature in patients with osteonecrosis of the femoral head.Metabolomics : Official journal of the Metabolomic Society · 2022Article
- Osteoimmunology and osteonecrosis of the femoral head.Bone & joint research · 2022Article
- Identification of Inflammation-Related Genes and Exploration of Regulatory Mechanisms in Patients with Osteonecrosis of the Femoral Head.BioMed research international · 2022Article
- Non-coding RNA Identification in Osteonecrosis of the Femoral Head Using Competitive Endogenous RNA Network Analysis.Orthopaedic surgery · 2021Article
- Urinary miRNAs as biomarkers for idiopathic osteonecrosis of femoral head: A multicentre study.Journal of orthopaedic translation · 2021Article
- Extracorporeal Shockwave Therapy Modulates the Expressions of Proinflammatory Cytokines IL33 and IL17A, and Their Receptors ST2 and IL17RA, within the Articular Cartilage in Early Avascular Necrosis of the Femoral Head in a Rat Model.Mediators of inflammation · 2021Article
- Development and validation of a nomogram for predicting the probability of nontraumatic osteonecrosis of the femoral head in Chinese population.Scientific reports · 2020Article
- Serum glycosylation characterization of osteonecrosis of the femoral head by mass spectrometry.European journal of mass spectrometry (Chichester, England) · 2018Article
- Role of autophagy in tumor necrosis factor-α-induced apoptosis of osteoblast cells.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2017Article
- Cirrhosis is a risk factor for total hip arthroplasty for avascular necrosis.Acta orthopaedica · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study examines plasma interleukin 33 (IL-33) levels in patients with osteonecrosis of the femoral head (ONFH) and explores the possible use of IL-33 as a marker for early diagnosis and progression of ONFH.
methodsOne hundred twenty-five ONFH patients and 126 control subjects were recruited for this study. The plasma IL-33 levels were measured using a commercially available enzyme-linked immunosorbent assay kit. Effects of disease stage and risk factors on IL-33 level were also assessed.
resultsPlasma IL-33 levels were significantly higher in the 125 ONFH patients (174.33 [SD, 65.73] pg/mL) than in the 126 control subjects (90.50 [SD, 25.17] pg/mL, P < 0.001). Plasma IL-33 levels were significantly higher in patients with stage III/IV ONFH (184.17 [SD, 43.75] pg/mL) than in patients with stage I/II ONFH (158.24 [SD, 50.11] pg/mL, P < 0.001). There was no significant difference in IL-33 levels between alcohol-induced, idiopathic, and steroid-induced cases.
conclusionsPlasma IL-33 may be an alarmin for ONFH, and its levels may be related to disease progression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.