Evidence map›Paper›PMID 24430170›Full record

ReviewCurrent urology reports2014

Lymphotropic nanoparticle-enhanced MRI in prostate cancer: value and therapeutic potential.

Ansje S Fortuin, Robert Jan Smeenk, Hanneke J M Meijer, Alfred J Witjes, Jelle O Barentsz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Imaging of distant metastases of prostate cancer.Medical oncology (Northwood, London, England) · 2018
    Review
  11. Review
  12. Article
  13. Ultra-small superparamagnetic iron oxides for metastatic lymph node detection: back on the block.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2018
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Prostate MRI - an update for the referring urologist.Central European journal of urology · 2016
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ansje S FortuinDepartment of Radiology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands, Ansje.fortuin@radboudumc.nl.
Robert Jan Smeenk
Hanneke J M Meijer
Alfred J Witjes
Jelle O Barentsz
Radboud University Nijmegen · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nodal staging in prostate cancer is suboptimal both with respect to current imaging modalities and pelvic lymph node dissection, and thus other techniques are being explored. Lymphotropic nanoparticle-enhanced MRI, also called magnetic resonance lymphography (MRL), is a technique that has shown high sensitivity (65-92 %) and excellent specificity (93-98 %) in detecting prostate cancer lymph node metastases. This technique aids in the detection of metastases in non-enlarged small nodes. MRL has been useful in determining the location and pathways of spread in nodal chains. Knowledge of the location of lymph node involvement is important for decisions regarding appropriate therapeutic options, such as image-guided therapy.. A geographic miss in radiotherapy can be avoided with the use of MRL-guided focal therapy. This paper provides an overview of current literature, lessons learned, and new therapeutic options with nanoparticle-enhanced MRI.

Indexed as

Contrast MediaDextransMagnetite NanoparticlesHumansLymphatic IrradiationLymphatic MetastasisLymph Node ExcisionLymphographyMagnetic Resonance ImagingMaleNeoplasm StagingProstatic NeoplasmsRadiotherapy, Image-GuidedSensitivity and SpecificityContrast MediaDextransferumoxtran-10Magnetite Nanoparticles

Identifiers

PMID24430170
OpenAlexW1995080742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.