Evidence map›Paper›PMID 24430116›Full record

ArticleNeuroradiology2014

Temporal changes in CT perfusion values before and after cranioplasty in patients without symptoms related to external decompression: a pilot study.

Silvio Sarubbo, Francesco Latini, Stefano Ceruti, Arturo Chieregato, Christopher d'Esterre, Ting-Yim Lee, Michele Cavallo, Enrico Fainardi

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Silvio SarubboNeurosurgery Unit, Department of Neurosciences, "S. Chiara" Hospital, APSS Trento, Trento, Italy.
Francesco Latini
Stefano Ceruti
Arturo Chieregato
Christopher d'Esterre
Ting-Yim Lee
Michele Cavallo
Enrico Fainardi
Ospedale Sant'Anna · ITArcispedale Sant'Anna · ITAzienda Ospedaliero-Universitaria Careggi · ITLawson Health Research Institute · CAOspedale Santa Chiara · ITUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLittle is known about hemodynamic disturbances affecting cerebral hemispheres in traumatic brain injury (TBI) after cranioplasty.

methodsWe prospectively investigated six stable TBI patients who underwent cranioplasty more than 90 days after effective decompressive craniectomy. Computerized tomography perfusion (CTP) studies and evaluation of clinical outcome were performed for each patient before cranioplasty and at 7 days and 3 months after surgery. Cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) were measured in multiple cortical circular regions positioned in cranioplasty-treated and contralateral hemispheres.

resultsNeither complications associated with cranioplasty nor changes in outcome were observed. On the treated side, CBF and CBV values were higher before and 7 days after cranioplasty than at 3 months after surgery, whereas MTT values were lower at 7 days than at 3 months after surgical treatment.

conclusionsOur results indicate that cortical perfusion progressively declines in the cranioplasty treated hemisphere but remains stable in the contralateral hemisphere after surgery and suggest that CTP can represent a promising tool for a longitudinal analysis of hemodynamic abnormalities occurring in TBI patients after cranioplasty. In addition, these data imply a possible role of cranioplasty in restoring flow to meet the prevailing metabolic demand.

Indexed as

Cerebrovascular CirculationAdultAgedBlood Flow VelocityBrain InjuriesCerebral AngiographyCombined Modality TherapyCraniotomyDecompressive CraniectomyHumansMaleMiddle AgedTomography, X-Ray ComputedTreatment Outcome

Identifiers

PMID24430116
OpenAlexW2110659156

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.