ArticleLearning & memory (Cold Spring Harbor, N.Y.)2014
The role of rewarding and novel events in facilitating memory persistence in a separate spatial memory task.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Strain- and age-dependent divergence in mouse appetitive spatial learning and decision strategies.Frontiers in behavioral neuroscience · 2026Article
- Memory persistence enhancement by post-learning moderate exercise requires de novo protein synthesis in the dorsal hippocampus.PloS one · 2025Article
- Linking new information to a short-lasting memory trace induces consolidation in the hippocampus.iScience · 2024Article
- Rats show up to 72 h of significant retention for spatial memory in the radial maze.Learning & behavior · 2024Article
- Rodent maze studies: from following simple rules to complex map learning.Brain structure & function · 2024Review
- A behavioral tagging account of kinase contribution to memory formation after spaced aversive training.iScience · 2023Article
- Article
- Tag and capture: how salient experiences target and rescue nearby events in memory.Trends in cognitive sciences · 2022Review
- Behavioral and Cellular Tagging in Young and in Early Cognitive Aging.Frontiers in aging neuroscience · 2022Article
- Article
- Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Dopamine is associated with prioritization of reward-associated memories in Parkinson's disease.Brain : a journal of neurology · 2020Article
- A Dual Reward-Place Association Task to Study the Preferential Retention of Relevant Memories in Rats.Frontiers in behavioral neuroscience · 2020Article
- Decision-making Increases Episodic Memory via Postencoding Consolidation.Journal of cognitive neuroscience · 2019Article
- Novelty enhances memory persistence and remediates propranolol-induced deficit via reconsolidation.Neuropharmacology · 2018Article
- Behavioral tagging and capture: long-term memory decline in middle-aged rats.Neurobiology of aging · 2018Article
- Selectivity in Postencoding Connectivity with High-Level Visual Cortex Is Associated with Reward-Motivated Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Reward retroactively enhances memory consolidation for related items.Learning & memory (Cold Spring Harbor, N.Y.) · 2017Article
- Locus Coeruleus and Dopamine-Dependent Memory Consolidation.Neural plasticity · 2017Review
- Novelty during a late postacquisition time window attenuates the persistence of fear memory.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many insignificant events in our daily life are forgotten quickly but can be remembered for longer when other memory-modulating events occur before or after them. This phenomenon has been investigated in animal models in a protocol in which weak memories persist longer if exploration in a novel context is introduced around the time of memory encoding. This study aims to understand whether other types of rewarding or novel tasks, such as rewarded learning in a T-maze and novel object recognition, can also be effective memory-modulating events. Rats were trained in a delayed matching-to-place task to encode and retrieve food locations in an event arena. Weak encoding with only one food pellet at the sample location induced memory encoding but forgetting over 24 h. When this same weak encoding was followed by a rewarded task in a T-maze, the memory persisted for 24 h. Moreover, the same persistence of memory over 24 h could be achieved by exploration in a novel box or by a rewarded T-maze task after a "non-rewarded" weak encoding. When the one-pellet weak encoding was followed by novel object exploration, the memory did not persist at 24 h. Together, the results confirm that place encoding is possible without explicit reward, and that rewarded learning in a separate task lacking novelty can be an effective memory-modulating event. The behavioral and neurobiological implications are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.