ArticleMultidisciplinary respiratory medicine2014
Prevalence of allergen sensitization among patients with allergic diseases in Guangzhou, Southern China: a four-year observational study.
Article in Multidisciplinary respiratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Multifactorial analysis of allergen-specific IgE sensitization in children with allergic diseases in Suzhou, China.BMC pediatrics · 2026Article
- Prevalence and Patterns of Allergen Sensitization in Southern China: A Retrospective Analysis of 18,777 Routine Checkup Participants in Shenzhen.Journal of asthma and allergy · 2026Article
- Hospital-based patterns of allergen sensitization among 19,787 patients with suspected allergic diseases in Ningbo, China.Frontiers in public health · 2026Article
- Landscape of Aeroallergen Sensitization in Asia.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025Review
- Is There a Relationship Between Physical Performance Factors and Adverse Reactions to Foodstuffs? The ALASKA Study.Nutrients · 2024Article
- Allergens sensitization among children with allergic diseases in Shanghai, China: age and sex difference.Respiratory research · 2022Article
- Associations between sensitisation to allergens and allergic diseases: a hospital-based case-control study in China.BMJ open · 2022Article
- Fungal allergic sensitisation in young rural Zimbabwean children: Gut mycobiome and seroreactivity characteristics.Current research in microbial sciences · 2021Article
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- Mosquitoes: Important Sources of Allergens in the Tropics.Frontiers in allergy · 2021Review
- Prevalence of food-allergen and aeroallergen sensitization among people in Sichuan, Western China: An 8-year observational study.Journal of clinical laboratory analysis · 2019Observational
- Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules.World journal of methodology · 2018Article
- Allergen-specific IgE and IgG4 patterns among patients with different allergic diseases.The World Allergy Organization journal · 2018Article
- High cord blood CCL22/CXCL10 chemokine ratios precede allergic sensitization in early childhood.Oncotarget · 2017Article
- Sensitization to silk allergen among workers of silk filatures in India: a comparative study.Asia Pacific allergy · 2016Article
- Role of bilastine in the management of allergic rhinitis and urticaria: an Asia-Pacific consensus statement.Asia Pacific allergy · 2016Review
- Food allergy and related risk factors in 2540 preschool children: an epidemiological survey in Guangdong Province, southern China.World journal of pediatrics : WJP · 2015Article
- Quantitation of Blomia tropicalis allergen Blo t 5 in cereal and cereal-based foods consumed in the Nile Delta, Egypt.The American journal of tropical medicine and hygiene · 2015Article
- Sensitization to food and inhalant allergens in relation to atopic diseases in early childhood: a birth cohort study.PloS one · 2014Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe distribution of allergens may vary with different geographic areas, suggesting the importance of local epidemiological data to support evidence-based prevention and management of allergic diseases. We investigated the distribution of common allergens in allergic patients in Guangzhou, southern China.
methods7,047 patients with allergic symptoms were examined for serum sIgE to 15 common allergens in this region, based on the protocol of reversed enzyme allergosorbent test.
results4,869 (69.09%) of the subjects tested positive for sIgE to at least one of the 15 common allergens. There was no statistical difference in the overall rate of positive sIgE detection between males (3128/4523, 69.16%) and females (1741/2524, 68.98%). Der pteronyssinus and Der farinae were the most common aeroallergens, while eggs and cow's milk the most common food allergens, responsible for higher positive rates of sIgE responses. A good correlation in positive sIgE response was found between Der pteronyssinus and Der farinae. By age-group analysis, we noted several peaks of sensitization to certain allergens: Der pteronyssinus, Der farinae, and Blomiatropicalis at age between 9 and 12; Blattellagermanica and mosquito at age between 15 and 18, cow's milk before age 3; eggs and flour at age between 3 and 6; crabs and shrimps at age between 12 and 15. Along with older age, there was an ascending tendency in the overall positive rate of sIgE response to house dust mites among subjects who tested positive for sIgE to eggs or cow's milk.
conclusionsDer pteronyssinus, Der farinae, cow's milk, and eggs are major allergens in Guangzhou. Sensitization to eggs and cow's milk is more common at younger age, and then gives place to the increasing prevalence of sensitization to Der pteronyssinus and Der farinae at older age. Such a sequence of events may be a result of allergy march. Knowledge on the prevalence of allergen sensitization in different age groups would help early diagnosis and intervention of allergic diseases in this large geographical region.
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