ArticleWorld journal of emergency surgery : WJES2014
Acute appendicitis in the elderly: risk factors for perforation.
Article in World journal of emergency surgery : WJES, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 181 citations in OpenAlex.
- Swedish national guidelines for diagnosis and management of acute appendicitis in adults and children.BJS open · 2025Guideline
- Comparison of Clinical Features and Outcomes of Appendectomy in Elderly vs. Non-Elderly: A Systematic Review and Meta-Analysis.Frontiers in surgery · 2022Pooled it
- Laparoscopy versus open appendectomy for elderly patients, a meta-analysis and systematic review.BMC surgery · 2019Pooled it
- Considerations on Ultrasonographic Differentiation of Early Gangrenous and Uncomplicated Acute Appendicitis.Journal of clinical ultrasound : JCU · 2026Article
- Machine learning constructs a diagnostic prediction model for gangrenous perforation of acute appendicitis in elderly patients.BMC surgery · 2026Article
- Pneumatosis Intestinalis Secondary to Appendicitis: What Do We Know?Digestive diseases and sciences · 2025Review
- Regression analysis for intensive care unit (ICU) admission prediction in elderly patients with acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Observational
- Diagnostic Accuracy of a Machine Learning-Derived Appendicitis Score in Children: A Multicenter Validation Study.Children (Basel, Switzerland) · 2025Article
- Influence of sarcopenia and frailty in the management of elderly patients with acute appendicitis.World journal of clinical cases · 2024Article
- Construction of a clinical prediction model for complicated appendicitis based on machine learning techniques.Scientific reports · 2024Article
- Atypical Presentation and Diagnostic Challenges of Appendicitis in an 85-Year-Old Male: A Case Report.Cureus · 2024Article
- Acute Appendicitis in the Elderly: A Nationwide Retrospective Analysis.Journal of clinical medicine · 2024Article
- Mean platelet volume and total white blood cells as diagnostic biomarkers for acute appendicitis at Omdurman military hospital: a cross-sectional study - 2021.BMC gastroenterology · 2023Article
- Characteristics of appendicitis after immune checkpoint inhibitor therapy among cancer patients.Journal of cancer research and clinical oncology · 2023Article
- Eosinophil Granule Proteins Involvement in Acute Appendicitis-An Allergic Disease?International journal of molecular sciences · 2023Article
- Study of outcomes of perforated appendicitis in adults: a prospective cohort study.Annals of medicine and surgery (2012) · 2023Article
- Applicability of American College of Radiology Appropriateness Criteria Decision-Making Model for Acute Appendicitis Diagnosis in Children.Diagnostics (Basel, Switzerland) · 2022Article
- Acute appendicitis over the age of 50: The evaluation of the impact of clinical variables on operative and post-operative outcomes.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Diagnostic accuracy of Alvarado scoring system relative to histopathological diagnosis for acute appendicitis: A retrospective cohort study.Annals of medicine and surgery (2012) · 2022Article
- A comparative study of the RIPASA and Alvarado scores in geriatric patients diagnosed with acute appendicitis.Revista da Associacao Medica Brasileira (1992) · 2022Article
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6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute appendicitis is the most common surgical emergency and becomes serious when it perforates. Perforation is more frequent in the elderly patients. The aim of this study was to identify the risk factors of perforation in elderly patients who presented with acute appendicitis. METHODOLOGY: The medical records of 214 patients over the age of 60 years who had a pathologically confirmed diagnosis of acute appendicitis over a period of 10 years (2003-2013) were retrospectively reviewed. Patients were grouped into those with perforated and those with nonperforated appendicitis. Comparison was made between both groups in regard to demography, clinical presentation, and time delay to surgery, diagnosis, hospital stay and postoperative complications. Clinical assessment, Ultrasonography and Computerized tomography, in that order, were used for diagnosis. The incidence of perforation was also compared with a previous report from the same region 10 years earlier.
resultsDuring the study period, a total of 214 patients over the age of 60 years had acute appendicitis, 103 males and 111 females. Appendix was found perforated in 87 (41%) patients, 46 (53%) males and 41 (47%) females. Of all patients, 31% were diagnosed by clinical assessment alone, 40% needed US and 29% CT scan. Of all the risk factors studied, the patient's pre-hospital time delay was the most important risk factor for perforation. Perforation rate was not dependent on the presence of comorbid diseases or in-hospital time delay. Post operative complications occurred in 44 (21%) patients and they were three times more common in the perforated group, 33 (75%) patients in the perforated and 11 (25%) in the nonperforated group. There were 6 deaths (3%), 4 in the perforated and 2 in the nonperforated group.
conclusionAcute appendicitis in elderly patients is a serious disease that requires early diagnosis and treatment. Appendiceal Perforation increases both mortality and morbidity. All elderly patients presented to the hospital with abdominal pain should be admitted and investigated. The early use of CT scan can cut short the way to the appropriate treatment.
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