ArticleBMC musculoskeletal disorders2014
Kyphosis and paraspinal muscle composition in older men: a cross-sectional study for the Osteoporotic Fractures in Men (MrOS) research group.
Article in BMC musculoskeletal disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 45 citations in OpenAlex.
- Sex differences in response to targeted kyphosis specific exercise and posture training in community-dwelling older adults: a randomized controlled trial.BMC musculoskeletal disorders · 2017Trial
- Targeted spine strengthening exercise and posture training program to reduce hyperkyphosis in older adults: results from the study of hyperkyphosis, exercise, and function (SHEAF) randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Trial
- Feasibility and Reliability of an Automated Muscle Segmentation Pipeline Linking Thoracic Supine Kyphosis and Trunk Muscle-Fat% on CT.Tomography (Ann Arbor, Mich.) · 2026Article
- Characterizing aging-related genetic and physiological determinants of spinal curvature.Communications medicine · 2025Article
- Association between paraspinal muscle fat infiltration and regional kyphosis angle in thoracolumbar fracture patients: a retrospective study.Scientific reports · 2024Article
- The Correlation Between Paraspinal Muscular Morphology, Spinopelvic Parameters, and Back Pain: A Comparative Cohort Study.International journal of spine surgery · 2023Article
- Impact of spinal sagittal malalignment on locomotive syndrome and physical function in community-dwelling middle aged and older women.BMC musculoskeletal disorders · 2023Article
- Article
- Morphometry of lumbar muscles in the seated posture with weight-bearing MR scans.Journal of clinical orthopaedics and trauma · 2022Article
- Exploring thoracic kyphosis and incident fracture from vertebral morphology with high-intensity exercise in middle-aged and older men with osteopenia and osteoporosis: a secondary analysis of the LIFTMOR-M trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Preliminary investigation of spinal level and postural effects on thoracic muscle morphology with upright open MRI.JOR spine · 2021Article
- Factors Associated With Kyphosis and Kyphosis Progression in Older Men: The MrOS Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020Article
- Quantitative identification and segmentation repeatability of thoracic spinal muscle morphology.JOR spine · 2020Article
- Age-related fatty infiltration of lumbar paraspinal muscles: a normative reference database study in 516 Chinese females.Quantitative imaging in medicine and surgery · 2020Article
- Kyphosis and 3-year fall risk in community-dwelling older men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- The Clinical Relevance of Hyperkyphosis: A Narrative Review.Frontiers in endocrinology · 2020Review
- Sarcopenia is related to spinal sagittal imbalance in patients with spinopelvic mismatch.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the Framingham study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Analysis of kyphosis, vertebral fracture and bone mineral density measurement in women living in nursing homes.Saudi medical journal · 2018Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThe prevalence of hyperkyphosis is increased in older men; however, risk factors other than age and vertebral fractures are not well established. We previously reported that poor paraspinal muscle composition contributes to more severe kyphosis in a cohort of both older men and women.
methodsTo specifically evaluate this association in older men, we conducted a cross-sectional study to evaluate the association of paraspinal muscle composition and degree of thoracic kyphosis in an analytic cohort of 475 randomly selected participants from the Osteoporotic Fractures in Men (MrOS) study with baseline abdominal quantitative computed tomography (QCT) scans and plain thoracic radiographs. Baseline abdominal QCT scans were used to obtain abdominal body composition measurements of paraspinal muscle and adipose tissue distribution. Supine lateral spine radiographs were used to measure Cobb angle of kyphosis. We examined the linear association of muscle volume, fat volume and kyphosis using loess plots. Multivariate linear models were used to investigate the association between muscle and kyphosis using total muscle volume, as well as individual components of the total muscle volume, including adipose and muscle compartments alone, controlling for age, height, vertebral fractures, and total hip bone mineral density (BMD). We examined these associations among those with no prevalent vertebral fracture and those with BMI < 30 kg/m2.
resultsAmong men in the analytic cohort, means (SD) were 74 (SD = 5.9) years for age, and 37.5 (SD = 11.9) degrees for Cobb angle of kyphosis. Men in the lowest tertile of total paraspinal muscle volume had greater mean Cobb angle than men in the highest tertile, although test of linear trend across tertiles did not reach statistical significance. Neither lower paraspinal skeletal muscle volume (p-trend = 0.08), or IMAT (p-trend = 0.96) was associated with greater kyphosis. Results were similar among those with no prevalent vertebral fractures. However, among men with BMI < 30 kg/m2, those in the lowest tertile of paraspinal muscle volume had greater adjusted mean kyphosis (40.0, 95% CI: 37.8 - 42.1) compared to the highest tertile (36.3, 95% CI: 34.2 - 38.4).
conclusionsThese results suggest that differences in body composition may potentially influence kyphosis.
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