Evidence map›Paper›PMID 24427545›Full record

ReviewOncoimmunology2013

Myeloid-derived suppressor cells: Cellular missiles to target tumors.

Dinesh Chandra, Claudia Gravekamp

Open access · goldAbstract readReview
In one paragraph

Review in Oncoimmunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Fates of CD8+ T cells in Tumor Microenvironment.Computational and structural biotechnology journal · 2019
    Review
  7. Article
  8. Article
  9. White paper on microbial anti-cancer therapy and prevention.Journal for immunotherapy of cancer · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Myeloid-derived suppressor cells in B cell malignancies.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dinesh ChandraAlbert Einstein College of Medicine; Department of Microbiology and Immunology; Bronx, NY USA.
Claudia GravekampAlbert Einstein College of Medicine; Department of Microbiology and Immunology; Bronx, NY USA.
Albert Einstein College of Medicine · USThe Bronx Defenders · US

Funding

Training in Aging ResearchT32AG023475 · NIA · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI NIR J BARZILAI, DEREK Major HUFFMAN · 2004 to 2026
$8.6M
DNA vaccines for metastatic breat cancer at old ageR01AG023096 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI GRAVEKAMP, CLAUDIA · 2004 to 2010
$1.2M
NIA NIH HHS R01 AG023096NIA NIH HHS T32 AG023475
6 · The paper itself

Abstract

While conventional anticancer therapies, including surgical resection, radiotherapy, and/or chemotherapy, are relatively efficient at eliminating primary tumors, these treatment modalities are largely ineffective against metastases. At least in part, this reflects the rather inefficient delivery of conventional anticancer agents to metastatic lesions. We have recently demonstrated that myeloid-derived suppressor cells (MDSCs) can be used as cellular missiles to selectively deliver a radioisotope-coupled attenuated variant of

Indexed as

Cancer vaccineListeriaMDSCtargeted therapyTumor microenvironment

Identifiers

PMID24427545
PMCPMC3890360
OpenAlexW1985823203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.