Evidence map›Paper›PMID 24427542›Full record

ReviewInterface focus2013

New generation of magnetic and luminescent nanoparticles for in vivo real-time imaging.

Lise-Marie Lacroix, Fabien Delpech, Céline Nayral, Sébastien Lachaize, Bruno Chaudret

Open access · bronzeAbstract readReview
In one paragraph

Review in Interface focus, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Functional imaging for regenerative medicine.Stem cell research & therapy · 2016
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lise-Marie LacroixINSA, UPS, LPCNO (Laboratoire de Physique et Chimie des Nano-Objets) , Université de Toulouse , Toulouse 31077 France ; UMR 5215, LPCNO , CNRS , Toulouse 31077 , France.
Fabien DelpechINSA, UPS, LPCNO (Laboratoire de Physique et Chimie des Nano-Objets) , Université de Toulouse , Toulouse 31077 France ; UMR 5215, LPCNO , CNRS , Toulouse 31077 , France.
Céline NayralINSA, UPS, LPCNO (Laboratoire de Physique et Chimie des Nano-Objets) , Université de Toulouse , Toulouse 31077 France ; UMR 5215, LPCNO , CNRS , Toulouse 31077 , France.
Sébastien LachaizeINSA, UPS, LPCNO (Laboratoire de Physique et Chimie des Nano-Objets) , Université de Toulouse , Toulouse 31077 France ; UMR 5215, LPCNO , CNRS , Toulouse 31077 , France.
Bruno ChaudretINSA, UPS, LPCNO (Laboratoire de Physique et Chimie des Nano-Objets) , Université de Toulouse , Toulouse 31077 France ; UMR 5215, LPCNO , CNRS , Toulouse 31077 , France.
Canadian Nautical Research Society · CACentre National de la Recherche Scientifique · FRSciences Po Toulouse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new generation of optimized contrast agents is emerging, based on metallic nanoparticles (NPs) and semiconductor nanocrystals for, respectively, magnetic resonance imaging (MRI) and near-infrared (NIR) fluorescent imaging techniques. Compared with established contrast agents, such as iron oxide NPs or organic dyes, these NPs benefit from several advantages: their magnetic and optical properties can be tuned through size, shape and composition engineering, their efficiency can exceed by several orders of magnitude that of contrast agents clinically used, their surface can be modified to incorporate specific targeting agents and antifolding polymers to increase blood circulation time and tumour recognition, and they can possibly be integrated in complex architecture to yield multi-modal imaging agents. In this review, we will report the materials of choice based on the understanding of the basic physics of NIR and MRI techniques and their corresponding syntheses as NPs. Surface engineering, water transfer and specific targeting will be highlighted prior to their first use for in vivo real-time imaging. Highly efficient NPs that are safer and target specific are likely to enter clinical application in a near future.

Indexed as

contrast agentscore-shellluminescent nanocrystalsmagnetic resonance imagingnear-infraredquantum dots

Identifiers

PMID24427542
PMCPMC3638419
OpenAlexW2104551992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.