ReviewInternational journal of clinical and experimental pathology2014
Primary thyroid T-lymphoblastic lymphoma: a case report and review of the literature.
Review in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Primary thyroid diffuse large B-cell lymphoma: fine needle aspiration and histological correlation.Journal of pathology and translational medicine · 2025Article
- Spontaneous T-cell lymphoblastic lymphoma in a young ICR mouse: a case report.Journal of toxicologic pathology · 2025Article
- Integration of Single-Cell RNA Sequencing Data and Bulk Sequencing Data to Characterise the CD8+ T-Cell Exhaustion Mediated Immune Microenvironment in CRC.Journal of cellular and molecular medicine · 2025Article
- Primary Thyroid Lymphoma: A Retrospective-Observational Study in a Single Institutional Center.Medicina (Kaunas, Lithuania) · 2024Observational
- [Ultrasound-guided core-needle biopsy diagnosis of thyroid T-cell lymphoma: a case report].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Article
- Morphological and immunohistochemical approaches to the diagnosis of Hashimoto thyroiditis and mucosa associated lymphoid tissue lymphomas: An audit.Rare tumors · 2020Article
- Dyspnea after thyroidectomy induced by intratracheal lymphoma: A case report.Molecular and clinical oncology · 2019Article
- Primary thyroid lymphoma: A case report and review of the literature.Annals of medicine and surgery (2012) · 2017Article
- T-cell Lymphoma of Thyroid Gland with Lennert Type of Morphology: A Case Report and Review of the Literature.Head and neck pathology · 2016Review
- Unusual presentation of primary T-cell lymphoblastic lymphoma: description of two cases.Diagnostic pathology · 2014Article
- Primary Diffuse B-Cell Thyroid Lymphoma: Case Report and Literature Review.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most thyroid lymphomas are B-lineage, and T-cell lymphomas are rare. Here, we report a case of primary T-cell lymphoblastic lymphoma (T-LBL) of the thyroid gland. A 15-year-old boy presented with a painless thyroid mass. Ultrasonographic examination revealed a hypoechoic thyroid nodule measuring 4.6 cm × 1.9 cm × 3.4 cm. The thyroid function and antibodies were normal. Hemithyroidectomy was performed. Intraoperative frozen section was suggestive of malignant lymphoma. Histological examination showed diffuse round to oval medium sized cells with high nuclear/cytoplasmic ratio, finely dispersed chromatin, scanty cytoplasm, and numerous mitoses. Immunohistochemical studies revealed malignant cells were positive for terminal deoxynucleotidyltransferase, CD5, CD7, CD8, CD10, CD45RO, CD99, CD79a, CD3, CD1a and Ki-67 (>40%) and negative for CD34, CD20, BCL6, CD23, BCL2, Pax5 and EBV. A diagnosis of thyroid T-LBL was made. The patient was treated by intensive chemotherapy followed by allogeneic hematopoietic stem cell transplantation and has been in event-free survival for 65 months. The patient was unique because no cases of thyroid T-LBL have been previously reported, to our knowledge. Moreover, intensive chemotherapy followed by alloHSCT might be one of the adoptive options in therapy for this aggressive disease.
Indexed as
Identifiers
24427370PMC3885504W89399656What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.