ArticlePloS one2014
Natural history of perceived food hypersensitivity and IgE sensitisation to food allergens in a cohort of adults.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pooled it
- Parallel reductions of IgE and exhaled nitric oxide after optimized anti-inflammatory asthma treatment.Immunity, inflammation and disease · 2016Trial
- Food allergy outside the eight big foods in Europe: A systematic review and meta-analysis.Clinical and translational allergy · 2024Review
- Food hypersensitivity: an examination of factors influencing symptoms and temporal changes in the prevalence of sensitization in an adult sample.European journal of clinical nutrition · 2023Article
- Soy Gly m 8 sIgE Has Limited Value in the Diagnosis of Soy Allergy in Peanut Ara h 2-Sensitized Adults.International archives of allergy and immunology · 2023Article
- Phenotypic characterization of childhood- and adult-onset food allergy among adults in the United States.The journal of allergy and clinical immunology. Global · 2022Article
- Ultra-processed foods and allergic symptoms among children and adults in the United States: A population-based analysis of NHANES 2005-2006.Frontiers in public health · 2022Article
- Relationship between longitudinal changes in type-2 inflammation, immunoglobulin E sensitization, and clinical outcomes in young asthmatics.Clinical and translational allergy · 2021Article
- Prevalence of food hypersensitivity in relation to IgE sensitisation to common food allergens among the general adult population in West Sweden.Clinical and translational allergy · 2019Article
- Immunological Processes Driving IgE Sensitisation and Disease Development in Males and Females.International journal of molecular sciences · 2018Review
- Changes over Time in IgE Sensitization to Allergens of the Fish Parasite Anisakis spp.PLoS neglected tropical diseases · 2016Article
- The development of a standardised diet history tool to support the diagnosis of food allergy.Clinical and translational allergy · 2015Article
- Self-reported adverse reactions and IgE sensitization to common foods in adults with asthma.Clinical and translational allergy · 2015Article
- High incidence and remission of reported food hypersensitivity in Swedish children followed from 8 to 12 years of age - a population based cohort study.Clinical and translational allergy · 2014Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo longitudinal studies exist on the natural history of food hypersensitivity and IgE sensitisation to food allergens in adults.
objectiveTo examine the natural history of food hypersensitivity, the natural history of IgE sensitisation to food allergens and to investigate the risk factors for new onset food hypersensitivity.
methodsFood hypersensitivity was questionnaire-assessed in 2307 individuals (aged 20-45 years) from Iceland and Sweden during the European Community Respiratory Health Survey both at baseline and follow-up 9 years later. IgE food and aeroallergen sensitisation were assessed in a subgroup of these individuals (n = 807). Values of 0.35 kU/L and above were regarded as positive sensitisation.
resultsFood hypersensitivity was reported by 21% of the subjects and this proportion remained unchanged at follow-up (p = 0.58). Fruits, nuts and vegetables were the three most common causes of food hypersensitivity, with a similar prevalence at baseline and follow-up. The prevalence IgE sensitisation to food allergens decreased in general by 56% (p<0.001) and IgE sensitisation to peanut decreased in particular by 67% (p = 0.003). The prevalence of timothy grass IgE sensitisation decreased by 15% (p = 0.003) while cat, mite and birch IgE sensitisation did not decrease significantly. Female sex, rhinitis, eczema and presence of IgE sensitisation to aeroallergens were independently associated with new onset food hypersensitivity.
conclusionThe prevalence of food hypersensitivity remained unchanged while the prevalence of IgE sensitisation to food allergens decreased in adults over a 9-year follow-up period. The decrease in prevalence of IgE sensitisation to food allergens was considerably larger than the change in prevalence of IgE sensitisation to aeroallergens.
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