ReviewFrontiers in cellular neuroscience2014
The role of microRNAs in regulating neuronal connectivity.
Review in Frontiers in cellular neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Two intrinsic timing mechanisms set start and end times for dendritic arborization of a nociceptive neuron.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A 3D Fiber-Hydrogel Based Non-Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- A eutherian-specific microRNA controls the translation of Satb2 in a model of cortical differentiation.Stem cell reports · 2021Article
- Modelling and Refining Neuronal Circuits with Guidance Cues: Involvement of Semaphorins.International journal of molecular sciences · 2021Review
- miR-195-5p Regulates the Phenotype Switch of CCSM Cells by Targeting Smad7.Sexual medicine · 2021Article
- Neuroprotective effects of human amniotic fluid stem cells-derived secretome in an ischemia/reperfusion model.Stem cells translational medicine · 2021Article
- Downregulation of microRNA‑29c reduces pain after child delivery by activating the oxytocin‑GABA pathway.Molecular medicine reports · 2020Article
- Emerging Roles for 3' UTRs in Neurons.International journal of molecular sciences · 2020Review
- MicroRNA sequencing of rat hippocampus and human biofluids identifies acute, chronic, focal and diffuse traumatic brain injuries.Scientific reports · 2020Article
- The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology.Molecular neurobiology · 2019Article
- Brain Functional Reserve in the Context of Neuroplasticity after Stroke.Neural plasticity · 2019Review
- miR-137 Affects Vaginal Lubrication in Female Sexual Dysfunction by Targeting Aquaporin-2.Sexual medicine · 2018Article
- Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity.Neurotoxicology · 2018Review
- Timing of neuronal plasticity in development and aging.Wiley interdisciplinary reviews. Developmental biology · 2018Review
- Gene set enrichment analysis: A genome-wide expression profile-based strategy for discovering functional microRNA-disease relationships.The Journal of international medical research · 2018Article
- Recent advances in branching mechanisms underlying neuronal morphogenesis.F1000Research · 2018Review
- Axonal microRNAs: localization, function and regulatory mechanism during axon development.Journal of molecular cell biology · 2017Review
- Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects.Frontiers in pharmacology · 2017Review
- Axonal localization and mitochondrial association of precursor microRNA 338.Cellular and molecular life sciences : CMLS · 2016Article
- Cellular and molecular introduction to brain development.Neurobiology of disease · 2016Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The assembly of functional neural circuits is critical for complex thoughts, behavior and general brain function. Precise construction of neural circuits requires orderly transition of sequential events from axon outgrowth, pathfinding, branching, to synaptogenesis. Each of these steps is required to be tightly regulated in order to achieve meticulous formation of neuronal connections. MicroRNAs (miRNAs), which silence gene expression post-transcriptionally via either inhibition of translation or destabilization of messenger RNAs, have emerged as key regulators of neuronal connectivity. The expression of miRNAs in neurons is often temporally and spatially regulated, providing critical timing and local mechanisms that prime neuronal growth cones for dynamic responses to extrinsic cues. Here we summarize recent findings of miRNA regulation of neuronal connectivity in a variety of experimental platforms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.