Evidence map›Paper›PMID 24426270›Full record

ArticleIndian journal of virology : an official organ of Indian Virological Society2013

Development of murine models to study Hepatitis C virus induced liver pathogenesis.

Madiha Khalid, Sobia Manzoor, Muhammad Imran, Muqddas Tariq, Javed Ashraf, Qazi Laeeque Ahmed, Waseem Ashraf, Fahed Parvaiz, Muhammad Ashraf

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of virology : an official organ of Indian Virological Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Madiha KhalidAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Sobia ManzoorAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Muhammad ImranAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Muqddas TariqAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Javed AshrafIslam Medical and Dental College, Sialkot, Pakistan.
Qazi Laeeque AhmedAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Waseem AshrafAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Fahed ParvaizAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
Muhammad AshrafAtta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad, 44000 Pakistan.
University of the Sciences · USKarachi Medical and Dental College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is involved in different liver pathologies worldwide. In contemporary scenario, HCV treatment is lagging behind owing to absence of vaccines against virus. The only consideration for HCV treatment is pegylated interferon-alpha and ribavirin that results in sustained virological response in 50 % of patients. Two feasible hosts for HCV infection are chimpanzee and humans. For decades, chimpanzees are sole host to study HCV pathogenesis, but their use is limited due to ethical issues. The dilemma behind HCV therapy is the need of sustainable animal models that can help simulate in vivo conditions. We have assembled recent advances in animal models to study liver diseases for targeted therapy.

Indexed as

Hepatitis C virusLiver pathogenisisMurine models

Identifiers

PMID24426270
PMCPMC3784905
OpenAlexW2037703029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.