Evidence map›Paper›PMID 24426244›Full record

ArticleIndian journal of clinical biochemistry : IJCB2013

Study of hormone receptors and epidermal growth factor expression in invasive breast cancers in a cohort of Western India.

Hardik Dodiya, Amit Patel, Dipal Patel, Ashish Kaushal, D G Vijay

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation of Immunohistochemical Profile of Breast Cancer for Prognostics and Therapeutic Use.Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hardik DodiyaDepartment of Clinical Research and Development, Aastha Oncology Associates, HCG-Medisurge Hospitals Private Limited, Ahmedabad, 380006 Gujarat India.
Amit PatelDepartment of Clinical Research and Development, Aastha Oncology Associates, HCG-Medisurge Hospitals Private Limited, Ahmedabad, 380006 Gujarat India.
Dipal PatelDepartment of Clinical Research and Development, Aastha Oncology Associates, HCG-Medisurge Hospitals Private Limited, Ahmedabad, 380006 Gujarat India.
Ashish KaushalDepartment of Clinical Research and Development, Aastha Oncology Associates, HCG-Medisurge Hospitals Private Limited, Ahmedabad, 380006 Gujarat India.
D G VijayDepartment of Clinical Research and Development, Aastha Oncology Associates, HCG-Medisurge Hospitals Private Limited, Ahmedabad, 380006 Gujarat India.
Ahmedabad Civil Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of study was to evaluate and correlate the pathological characteristics of breast cancer patients with estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her2/neu) detected by immunohistochemistry and/or fluorescent in situ hybridization method. We have conducted 2 year study of 204 cases of breast cancer at HCG-Medisurge Hospitals, Ahmedabad from 2009 to 2011. Significant correlation was found in ER and PR expression whereas no correlation was found in hormonal receptors and Her2/neu expression. ER and PR positivity increased with advancing age in breast carcinoma patients while not affecting Her2/neu expression. The expression of hormone receptors were higher in infiltrating lobular carcinoma and infiltrating duct carcinoma subtypes of breast carcinoma as compared to other subtypes such medullary and in situ carcinoma. High-grade carcinoma patients were predominantly ER/PR negative and Her2/neu positive as compared to lower grade breast carcinoma whereas high-stage carcinoma patients were ER/PR positive and Her2/neu positive as compared to lower stage breast carcinoma.

Indexed as

Estrogen receptorsHuman epidermal growth factor receptorsProgesterone receptors

Identifiers

PMID24426244
PMCPMC3783920
OpenAlexW2010455531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.